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尼日利亚幼儿腹泻、咳嗽和发烧的发病率。

Morbidity from diarrhoea, cough and fever among young children in Nigeria.

作者信息

Kandala N-B, Ji C, Stallard N, Stranges S, Cappuccio F P

机构信息

Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, Clifford Bridge Road, Coventry CV2 2DX, U.K.

出版信息

Ann Trop Med Parasitol. 2008 Jul;102(5):427-45. doi: 10.1179/136485908X300797.

Abstract

Diarrhoea, cough and fever are the leading causes of childhood morbidity and mortality in sub-Saharan Africa. Despite it being a determinant of mortality in many developing countries, geographical location has seldom been considered as an explanatory factor for the large regional variations seen in the childhood morbidity attributed to these causes in this area. The relevant data collected in two Nigerian Demographic and Health Surveys, one in 1999 and the other in 2003, have now therefore been analysed and compared. The aim was to reveal and explore inequalities in the health of Nigerian children by mapping the spatial distribution of childhood morbidity associated with recent diarrhoea, cough and fever and accounting for important risk factors, using a Bayesian geo-additive model based on Markov-chain-Monte-Carlo techniques. Although the overall prevalences of recent diarrhoea, cough and fever recorded in 1999 (among children aged <3 years) were similar to those seen in 2003 (among children aged <5 years), the mapping of residual spatial effects indicated that, in each survey, the morbidity attributable to each of these causes varied, differently, at state level. Place of birth (hospital v. other), type of feeding (breastfed only v. other), parental education, maternal visits to antenatal clinics, household economic status, marital status of mother and place of residence were each significantly associated with the childhood morbidity investigated. In both surveys, children from urban areas were found to have a significantly lower risk of fever than their rural counterparts. Most other factors affecting diarrhoea, cough and fever differed in the two surveys. The risk of developing each of these three conditions increased in the first 6-8 months after birth but then gradually declined. The analysis explained a significant share of the pronounced residual spatial effects. Maps showing the prevalences of diarrhoea, cough and fever in young children across Nigeria were generated during this study. Such maps should facilitate the development of policies to fulfil the Millennium Development Goals in Nigeria and throughout sub-Saharan Africa.

摘要

腹泻、咳嗽和发烧是撒哈拉以南非洲地区儿童发病和死亡的主要原因。尽管地理位置在许多发展中国家是死亡率的一个决定因素,但在该地区,由这些原因导致的儿童发病率存在很大的区域差异,地理位置却很少被视为一个解释因素。因此,现在对1999年和2003年两次尼日利亚人口与健康调查收集的相关数据进行了分析和比较。目的是通过绘制与近期腹泻、咳嗽和发烧相关的儿童发病率的空间分布,并考虑重要的风险因素,利用基于马尔可夫链蒙特卡罗技术的贝叶斯地理加性模型,揭示和探索尼日利亚儿童健康方面的不平等。尽管1999年(3岁以下儿童)记录的近期腹泻、咳嗽和发烧的总体患病率与2003年(5岁以下儿童)相似,但剩余空间效应的映射表明,在每次调查中,这些原因导致的发病率在州一级存在不同程度的差异。出生地点(医院与其他)、喂养方式(仅母乳喂养与其他)、父母教育程度、母亲产前检查次数、家庭经济状况、母亲婚姻状况和居住地点均与所调查的儿童发病率显著相关。在两次调查中,发现城市地区的儿童发烧风险明显低于农村儿童。影响腹泻、咳嗽和发烧的大多数其他因素在两次调查中有所不同。这三种疾病的发病风险在出生后的前6 - 8个月增加,但随后逐渐下降。该分析解释了显著的剩余空间效应中的很大一部分。在这项研究中生成了显示尼日利亚各地幼儿腹泻、咳嗽和发烧患病率的地图。这些地图应有助于制定政策,以实现尼日利亚和整个撒哈拉以南非洲地区的千年发展目标。

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