van Wyk B-E
Department of Botany and Plant Biotechnology, University of Johannesburg, P.O. Box 524, Auckland Park 2006, South Africa.
J Ethnopharmacol. 2008 Oct 28;119(3):342-55. doi: 10.1016/j.jep.2008.05.029. Epub 2008 Jun 3.
Commercially important indigenous medicinal plants of southern Africa are reviewed in the context of fundamental knowledge about their ethnobotany, phylogeny, genetics, taxonomy, biochemistry, chemical variation, reproductive biology and horticulture. The aim is to explore the rapidly increasing number of scientific publications and to investigate the need for further research.
The Scopus (Elsevier) reference system was used to investigate trends in the number of scientific publications and patents in 38 medicinal plant species. Fifteen species of special commercial interest were chosen for more detailed reviews: Agathosma betulina, Aloe ferox, Artemisia afra, Aspalathus linearis, Cyclopia genistoides, Harpagophytum procumbens, Hoodia gordonii, Hypoxis hemerocallidea, Lippia javanica, Mesembryanthemum tortuosum, Pelargonium sidoides, Siphonochilus aethiopicus, Sutherlandia frutescens, Warburgia salutaris and Xysmalobium undulatum.
In recent years there has been an upsurge in research and development of new medicinal products and new medicinal crops, as is shown by a rapid increase in the number of scientific publications and patents. Despite the fact that an estimated 10% of the plant species of the world is found in southern Africa, only a few have been fully commercialized and basic scientific information is often not available.
The limited available information indicates that some of the plants display remarkable regional variation in morphological, genetic and chemical characters that should be more thoroughly investigated. Basic biological information is needed to guide the rapidly accelerating commercialization process, especially the selection of superior clones, the development of new cultivars and the standardization of raw materials.
在关于南部非洲具有商业重要性的本土药用植物的民族植物学、系统发育、遗传学、分类学、生物化学、化学变异、生殖生物学和园艺学等基础知识的背景下,对这些植物进行综述。目的是探究科学出版物数量的快速增长情况,并调查进一步研究的必要性。
使用Scopus(爱思唯尔)参考文献系统来调查38种药用植物的科学出版物和专利数量趋势。选择了15种具有特殊商业价值的植物进行更详细的综述:南非香叶木、好望角芦荟、南非艾、线叶金雀花、圆叶金雀花、钩果草、蝴蝶亚仙人掌、黄苞竹芋、扭果日中花、香叶天竺葵、非洲吊灯花、埃塞俄比亚虹吸兰、少花麒麟菜、药用沃伯格樟和波叶马利筋。
近年来,新药用产品和新药用作物的研发出现热潮,科学出版物和专利数量迅速增加即表明了这一点。尽管世界上估计有10%的植物物种存在于南部非洲,但只有少数植物已完全商业化,而且往往缺乏基础科学信息。
有限的现有信息表明,一些植物在形态、遗传和化学特征方面表现出显著的区域差异,应进行更深入的研究。需要基础生物学信息来指导快速加速的商业化进程,特别是优良克隆的选择、新品种的开发和原材料的标准化。