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简短视频干预对性病门诊患者新发感染的影响。

Effect of a brief video intervention on incident infection among patients attending sexually transmitted disease clinics.

作者信息

Warner Lee, Klausner Jeffrey D, Rietmeijer Cornelis A, Malotte C Kevin, O'Donnell Lydia, Margolis Andrew D, Greenwood Gregory L, Richardson Doug, Vrungos Shelley, O'Donnell Carl R, Borkowf Craig B

机构信息

Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention , Atlanta, Georgia, United States of America.

出版信息

PLoS Med. 2008 Jun 24;5(6):e135. doi: 10.1371/journal.pmed.0050135.

Abstract

BACKGROUND

Sexually transmitted disease (STD) prevention remains a public health priority. Simple, practical interventions to reduce STD incidence that can be easily and inexpensively administered in high-volume clinical settings are needed. We evaluated whether a brief video, which contained STD prevention messages targeted to all patients in the waiting room, reduced acquisition of new infections after that clinic visit.

METHODS AND FINDINGS

In a controlled trial among patients attending three publicly funded STD clinics (one in each of three US cities) from December 2003 to August 2005, all patients (n = 38,635) were systematically assigned to either a theory-based 23-min video depicting couples overcoming barriers to safer sexual behaviors, or the standard waiting room environment. Condition assignment alternated every 4 wk and was determined by which condition (intervention or control) was in place in the clinic waiting room during the patient's first visit within the study period. An intent-to-treat analysis was used to compare STD incidence between intervention and control patients. The primary endpoint was time to diagnosis of incident laboratory-confirmed infections (gonorrhea, chlamydia, trichomoniasis, syphilis, and HIV), as identified through review of medical records and county STD surveillance registries. During 14.8 mo (average) of follow-up, 2,042 patients (5.3%) were diagnosed with incident STD (4.9%, intervention condition; 5.7%, control condition). In survival analysis, patients assigned to the intervention condition had significantly fewer STDs compared with the control condition (hazard ratio [HR], 0.91; 95% confidence interval [CI], 0.84 to 0.99).

CONCLUSIONS

Showing a brief video in STD clinic waiting rooms reduced new infections nearly 10% overall in three clinics. This simple, low-intensity intervention may be appropriate for adoption by clinics that serve similar patient populations.

TRIAL REGISTRATION

http://www.ClinicalTrials.gov (#NCT00137670).

摘要

背景

性传播疾病(STD)的预防仍然是公共卫生的重点。需要简单、实用的干预措施来降低性传播疾病的发病率,这些措施应能在大量临床环境中轻松且低成本地实施。我们评估了一段简短的视频,该视频包含针对候诊室所有患者的性传播疾病预防信息,是否能减少患者在该诊所就诊后新感染的发生。

方法与结果

在2003年12月至2005年8月期间,对就诊于三家公共资助的性传播疾病诊所(美国三个城市各一家)的患者进行了一项对照试验。所有患者(n = 38,635)被系统地分配到观看一段基于理论的23分钟视频,视频描绘了情侣克服安全性行为障碍的过程,或者被分配到标准的候诊室环境。每4周交替进行一次分组,分组依据是在研究期间患者首次就诊时诊所候诊室所处的状态(干预组或对照组)。采用意向性分析来比较干预组和对照组患者的性传播疾病发病率。主要终点是通过查阅病历和县级性传播疾病监测登记处确定的实验室确诊的新发感染(淋病、衣原体感染、滴虫病、梅毒和艾滋病毒)的诊断时间。在平均14.8个月的随访期间,2042名患者(5.3%)被诊断为新发性传播疾病(干预组为4.9%,对照组为5.7%)。在生存分析中,与对照组相比,分配到干预组的患者性传播疾病显著更少(风险比[HR],0.91;95%置信区间[CI],0.84至0.99)。

结论

在三家性传播疾病诊所的候诊室播放一段简短的视频,总体上新感染减少了近10%。这种简单、低强度的干预措施可能适合服务于类似患者群体的诊所采用。

试验注册

http://www.ClinicalTrials.gov(#NCT00137670)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d64/2504047/10217e0fe449/pmed.0050135.g001.jpg

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