Gladden L Bruce
Department of Kinesiology, Auburn University, Auburn, AL 36849-5323, United States.
Exerc Sport Sci Rev. 2008 Jul;36(3):109-15. doi: 10.1097/JES.0b013e31817c0038.
This year, 2008, marks the bicentennial of research into lactate metabolism in muscle. Berzelius linked lactate accumulation to exercise in 1807/1808 when he noted the presence of lactate in the muscles of "hunted stags." Today, the exact mechanism of intramuscular lactate oxidation and the relationship of lactate dehydrogenase to mitochondria remain unresolved as animated debate surrounds the intracellular lactate shuttle.
2008年是对肌肉中乳酸代谢研究的二百周年纪念。1807年/1808年，贝采利乌斯将乳酸积累与运动联系起来，当时他注意到“被追捕的雄鹿”肌肉中存在乳酸。如今，随着围绕细胞内乳酸穿梭的激烈争论，肌肉内乳酸氧化的确切机制以及乳酸脱氢酶与线粒体的关系仍未得到解决。
