Mazzoncini Joseph P, Crowell Christopher B, Kang Christopher S
Department of Emergency Medicine, Madigan Army Medical Center, Fort Lewis, Washington, USA.
J Emerg Med. 2010 May;38(4):456-9. doi: 10.1016/j.jemermed.2007.11.051. Epub 2008 Jun 27.
Human metapneumovirus (hMPV) is an important emerging respiratory pathogen, previously unreported in the Emergency Medicine literature. It is primarily associated with the clinical syndromes of bronchiolitis and pneumonia. hMPV may predispose to bacterial pneumonia; coinfection with respiratory syncytial virus may lead to increased severity of clinical disease, and complications include asthma and chronic obstructive pulmonary disease exacerbations. Given its high prevalence and potential clinical implications as these patients present to the Emergency Department with initial infection or subsequent complications, a better understanding of hMPV will aid in their care. We report the case of a 13-month old who developed lobar pneumonia 3 weeks after being diagnosed with hMPV. The epidemiology, clinical presentation, complications, and treatment of hMPV are then discussed.
人偏肺病毒(hMPV)是一种重要的新出现的呼吸道病原体,此前在急诊医学文献中未有报道。它主要与细支气管炎和肺炎的临床综合征相关。hMPV可能易引发细菌性肺炎;与呼吸道合胞病毒合并感染可能导致临床疾病严重程度增加,并发症包括哮喘和慢性阻塞性肺疾病急性加重。鉴于这些患者因初次感染或后续并发症就诊于急诊科时hMPV的高流行率及其潜在临床意义,更好地了解hMPV将有助于对他们的治疗。我们报告一例13个月大的患儿,在被诊断为hMPV 3周后发生了大叶性肺炎。随后讨论了hMPV的流行病学、临床表现、并发症及治疗。