Poland Gregory A, Johnson David R
Mayo Vaccine Research Group, Mayo Clinic, Rochester, Minnesota 55905, USA.
Am J Med. 2008 Jul;121(7 Suppl 2):S3-10. doi: 10.1016/j.amjmed.2008.05.002.
The burden of influenza on affected individuals and the healthcare system, as well as on society, is substantial. Although the supply of an effective and safe influenza vaccine was limited in previous years, advances in manufacture and distribution have alleviated such shortages. In most seasons, millions of doses go unused, and large numbers of unvaccinated, at-risk persons are left vulnerable to infection and its complications. According to insurance claims data, high-risk patients are seen by their healthcare providers on average 2.2 times between the peaks in vaccination (November) and in disease activity (February), yet they remain unvaccinated. The current 2- to 3-month time frame over which patients are traditionally immunized is too short to fully implement immunization recommendations and inconsistent with the duration of influenza activity. Both healthcare providers and patients should reevaluate their approach to influenza vaccination and recognize the need to extend the immunization time period into January and beyond. To increase influenza immunization rates, the Centers for Disease Control and Prevention (CDC) and other professional societies recommend an expanded immunization season, with vaccination offered at every opportunity between October and May.
流感给受影响的个人、医疗系统乃至社会带来的负担是巨大的。尽管过去几年有效且安全的流感疫苗供应有限,但生产和配送方面的进步缓解了此类短缺。在大多数季节,数百万剂疫苗未被使用,大量未接种疫苗的高危人群仍易感染流感及其并发症。根据保险理赔数据,高危患者在疫苗接种高峰(11月)和疾病活动高峰(2月)之间,平均看诊次数为2.2次,但他们仍未接种疫苗。传统上患者进行免疫接种的2至3个月时间框架太短,无法充分落实免疫接种建议,且与流感活动持续时间不一致。医疗服务提供者和患者都应重新评估他们对待流感疫苗接种的方式,并认识到有必要将免疫接种时间段延长至1月及以后。为提高流感疫苗接种率,美国疾病控制与预防中心(CDC)和其他专业协会建议延长免疫接种季节,在10月至5月期间抓住每个机会提供疫苗接种。