Canady Renée B, Bullen Bertha L, Holzman Claudia, Broman Clifford, Tian Yan
Ingham County Health Department, Lansing, Michigan 48909, USA.
Womens Health Issues. 2008 Jul-Aug;18(4):292-300. doi: 10.1016/j.whi.2008.04.003.
Depressive symptomatology during pregnancy has been associated with negative health outcomes for both the mother and child. This study examines the potential associations between depression and depressive symptoms in poor women and African-American women and their lifelong experiences of discrimination.
Data from 2,731 African-American and White participants in the Pregnancy Outcomes and Community Health Study were analyzed. Multiple regression analyses were used to investigate relations between depressive symptoms and total discrimination, and between depressive symptoms and 3 discrimination types (gender, race, and socioeconomic).
Initial results showed that African-American women had higher levels of depressive symptoms than White women. Self-reported total discrimination and discrimination types were each positively associated with depressive symptomatology in all women. After adjusting for sociodemographic characteristics (maternal age, education, employment status, partner status, and Medicaid status) and examining significant interactions, the race difference in depressive symptomatology was evident only in employed women. The addition of total discrimination to the multicovariate model eliminated race differences in the adjusted mean level of depressive symptoms. When the 3 discrimination types were modeled simultaneously with all other covariates, only gender and economic discrimination remained positively associated with depressive symptoms in African-American and White women.
These results should be cautiously interpreted because of 1) the study design--namely, ascertainment of maternal discrimination and depressive symptoms at a single time point; and 2) limitations of the discrimination measure. Despite these limitations, the study points to potential links between lifetime discrimination and depressive symptoms in pregnancy.
孕期的抑郁症状与母亲和孩子的不良健康结局相关。本研究考察贫困女性和非裔美国女性的抑郁与抑郁症状之间的潜在关联,以及她们一生的受歧视经历。
对参与“妊娠结局与社区健康研究”的2731名非裔美国人和白人参与者的数据进行分析。采用多元回归分析来研究抑郁症状与总体歧视之间的关系,以及抑郁症状与三种歧视类型(性别、种族和社会经济)之间的关系。
初步结果显示,非裔美国女性的抑郁症状水平高于白人女性。自我报告的总体歧视和歧视类型在所有女性中均与抑郁症状呈正相关。在调整社会人口学特征(母亲年龄、教育程度、就业状况、伴侣状况和医疗补助状况)并检验显著的交互作用后,抑郁症状的种族差异仅在就业女性中明显。在多变量模型中加入总体歧视后,抑郁症状调整后平均水平的种族差异消失。当将三种歧视类型与所有其他协变量同时建模时,只有性别和经济歧视在非裔美国女性和白人女性中仍与抑郁症状呈正相关。
由于1)研究设计——即在单一时间点确定母亲的歧视和抑郁症状;以及2)歧视测量的局限性,这些结果应谨慎解读。尽管存在这些局限性,但该研究指出了一生的歧视与孕期抑郁症状之间的潜在联系。