Cui X, Kim H-M, Kawashita M, Wang L, Xiong T, Kokubo T, Nakamura T
Institute of Metal Research, Chinese Academy of Sciences, Shenyang, China.
Dent Mater. 2009 Jan;25(1):80-6. doi: 10.1016/j.dental.2008.04.012. Epub 2008 Jul 2.
To research the crystal structure and surface morphology of anodic films on titanium metal in different electrolytes under various electrochemical conditions and investigate the effect of the crystal structure of the oxide films on apatite-forming ability in simulated body fluid (SBF).
Titanium oxide films were prepared using an anodic oxidation method on the surface of titanium metal in four different electrolytes: sulfuric acid, acetic acid, phosphoric acid and sodium sulfate solutions with different voltages for 1 min at room temperature.
Anodic films that consisted of rutile and/or anatase phases with porous structures were formed on titanium metal after anodizing in H(2)SO(4) and Na(2)SO(4) electrolytes, while amorphous titania films were produced after anodizing in CH(3)COOH and H(3)PO(4) electrolytes. Titanium metal with the anatase and/or rutile crystal structure films showed excellent apatite-forming ability and produced a compact apatite layer covering all the surface of titanium after soaking in SBF for 7d, but titanium metal with amorphous titania layers was not able to induce apatite formation.
The resultant apatite layer formed on titanium metal in SBF could enhance the bonding strength between living tissue and the implant. Anodic oxidation is believed to be an effective method for preparing bioactive titanium metal as an artificial bone substitute even under load-bearing conditions.
研究在不同电化学条件下，钛金属在不同电解液中阳极氧化膜的晶体结构和表面形貌，并探究氧化膜晶体结构对其在模拟体液（SBF）中磷灰石形成能力的影响。
采用阳极氧化法在钛金属表面于四种不同电解液中制备氧化钛膜，这四种电解液分别为硫酸、醋酸、磷酸和硫酸钠溶液，在室温下施加不同电压持续1分钟。
在硫酸和硫酸钠电解液中对钛金属进行阳极氧化后，形成了由金红石相和/或锐钛矿相组成且具有多孔结构的阳极氧化膜，而在醋酸和磷酸电解液中阳极氧化后则生成了非晶态二氧化钛膜。具有锐钛矿和/或金红石晶体结构膜的钛金属在SBF中浸泡7天后显示出优异的磷灰石形成能力，并在钛的整个表面生成了致密的磷灰石层，但具有非晶态二氧化钛层的钛金属无法诱导磷灰石形成。
在SBF中钛金属表面形成的磷灰石层可增强活体组织与植入物之间的结合强度。阳极氧化被认为是一种即使在承重条件下也能制备作为人工骨替代物的生物活性钛金属的有效方法。
