Schoenen J, Sianard-Gainko J, Lenaerts M
University Department of Neurology, CHR Citadelle University of Liege, Belgium.
Cephalalgia. 1991 May;11(2):97-9. doi: 10.1046/j.1468-2982.1991.1102097.x.
Serum and erythrocyte magnesium levels were screened between attacks in patients with migraine without aura (n = 38) and with aura (n = 6), and for comparison in a group of patients suffering from chronic tension-type headache (n = 25) as well as a group of neurological, non-headache patients (n = 19). Serum magnesium levels were not significantly different between the four groups of patients. In contrast, magnesium in erythrocytes was on average significantly reduced in patients with migraine without aura compared to the other groups. It is hypothesized that this reduction might be due to an abnormal regulation of intracellular magnesium possibly reflecting at the periphery changes observed in the brain of migraineurs.
在无先兆偏头痛患者（n = 38）和有先兆偏头痛患者（n = 6）发作间期筛查血清和红细胞镁水平，并与一组慢性紧张型头痛患者（n = 25）以及一组神经科非头痛患者（n = 19）进行比较。四组患者的血清镁水平无显著差异。相比之下，无先兆偏头痛患者红细胞中的镁平均水平相较于其他组显著降低。据推测，这种降低可能是由于细胞内镁的调节异常，这可能反映了偏头痛患者大脑中在周边观察到的变化。
