da Costa Morato Nery Débora, da Silva Carmelita Gomes, Mariani Diana, Fernandes Patrícia Neves, Pereira Marcos Dias, Panek Anita Dolly, Eleutherio Elis Cristina Araújo
Departamento de Bioquímica, Instituto de Química, UFRJ, 21941-909 Rio de Janeiro, RJ, Brazil.
Biochim Biophys Acta. 2008 Dec;1780(12):1408-11. doi: 10.1016/j.bbagen.2008.05.011. Epub 2008 Jun 5.
During menadione stress, trehalose was necessary intracellularly, but under H2O2, the sugar was required on the outside of the plasma membrane. The mechanism of protection involves minimizing the oxidative damage caused to both proteins and lipids, which would require the presence of trehalose on both sides of the lipid bilayer.
在甲萘醌胁迫下，海藻糖在细胞内是必需的，但在过氧化氢作用下，这种糖类在质膜外侧是必需的。保护机制包括将对蛋白质和脂质造成的氧化损伤降至最低，这需要在脂质双层的两侧都存在海藻糖。
