Okada K, Tobari I
Department of Ophthalmology, Ohashi Hospital, School of Medicine, Toho University, Tokyo, Japan.
J Cataract Refract Surg. 1991 May;17(3):319-23. doi: 10.1016/s0886-3350(13)80828-0.
Specular microscopy was performed to evaluate the postoperative cellular reaction on surface modified poly(methyl methacrylate) intraocular lenses (IOLs) (Ioptex Research, Inc., model U370) in 40 eyes of 36 patients who had extracapsular cataract extraction with implantation of the surface modified IOLs. The cellular elements observed were fibroblast-like cells, histiocytes, and giant cells. Gray amorphous depositions, part of which were sometimes recognized as interference fringes or interference colors, formed a layer in the center of the optics. These depositions were probably caused by the adsorption from aqueous humor. In subclinical cases, only a few histiocytes and giant cells were recognized in the optic center and the optic periphery was free of the cells during our observation. Within two months of surgery most of the cells had disappeared. In vivo specular microscopy showed no manufacturing defects on the implanted lenses. Our findings suggest that, although there was a postoperative cellular reaction on the surface modified IOLs, they were biocompatible.
对36例接受了囊外白内障摘除术并植入表面改性聚甲基丙烯酸甲酯人工晶状体（IOLs，Ioptex Research公司，型号U370）的患者的40只眼睛进行了镜面显微镜检查，以评估术后表面改性人工晶状体上的细胞反应。观察到的细胞成分有成纤维细胞样细胞、组织细胞和巨细胞。灰色无定形沉积物在光学部中心形成一层，部分沉积物有时被识别为干涉条纹或干涉色。这些沉积物可能是由房水吸附引起的。在亚临床病例中，在我们的观察期间，仅在光学部中心识别出少数组织细胞和巨细胞，光学部周边无细胞。术后两个月内，大多数细胞消失。体内镜面显微镜检查显示植入的人工晶状体没有制造缺陷。我们的研究结果表明，尽管表面改性人工晶状体术后有细胞反应，但它们具有生物相容性。
