Arýcan Ozer, Koç Kadriye, Ersoy Lütfiye
Kahramanmaras Sutcu Imam University Medical Faculty, Department of Dermatology, Kahramanmaras, Turkey.
Acta Dermatovenerol Alp Pannonica Adriat. 2008 Sep;17(3):129-32.
This study assesses clinical findings and coexisting dermatological and systemic diseases of Turkish vitiligo patients.
One hundred and thirteen patients were included in the study over a 2-year period. Patients were diagnosed by clinical findings and Wood's lamp. Each patient's age, sex, date of onset, first localization, clinical type, disease activity, coexisting systemic or dermatological diseases, and familial history were recorded. A complete blood count, routine biochemistry tests, serum vitamin B12 and folic acid, thyroid hormones, and complete urinalysis were done. All patients were examined by the outpatient psychiatric service.
The majority of patients were female (n = 60, 53.1%), and the rest males (n = 53, 46.9%). Their ages ranged from 2 to 76 years. Eighty-seven patients showed a progression of vitiligo. The age at onset of the condition varied from 6 months to 75 years. In 58 patients vitiligo was generalized, whereas in 47 it was localized. The most common site of onset was the upper limbs (38.1%), followed by the head and neck (24.8%), trunk (15%), lower limbs (13.3%), and genital area (8.8%). Leukotrichia was present in 21 patients; only 12 had a family history of vitiligo. The most common psychiatric diagnoses were depression (32.7%) and anxiety (15.9%). Coexisting cutaneous and systemic disorders were present in 22 patients.
The disease predominantly affects the younger population.
本研究评估土耳其白癜风患者的临床症状以及并存的皮肤和全身性疾病。
在两年时间里，113名患者纳入本研究。通过临床症状和伍德灯对患者进行诊断。记录每位患者的年龄、性别、发病日期、首发部位、临床类型、疾病活动度、并存的全身性或皮肤疾病以及家族史。进行了全血细胞计数、常规生化检查、血清维生素B12和叶酸、甲状腺激素以及尿常规检查。所有患者均接受门诊精神科检查。
大多数患者为女性（n = 60，53.1%），其余为男性（n = 53，46.9%）。他们的年龄在2岁至76岁之间。87名患者白癜风病情有进展。发病年龄从6个月至75岁不等。58名患者白癜风为泛发型，47名患者为局限型。最常见的发病部位是上肢（38.1%），其次是头颈部（24.8%）、躯干（15%）、下肢（13.3%）和生殖器部位（8.8%）。21名患者有白发；仅有12名患者有白癜风家族史。最常见的精神科诊断是抑郁症（32.7%）和焦虑症（15.9%）。22名患者并存皮肤和全身性疾病。
该疾病主要影响年轻人群。
