Quarto G, Sivero L, Somma P, De Rosa G, Mosella F, Nunziata G, Solimeno G, Benassai G
Department of General, Oncological and Videoassisted Surgery, Federico II University, Naples, Italy.
Minerva Gastroenterol Dietol. 2008 Sep;54(3):317-21.
Esophageal infections may be caused by diverse pathogens that alter the mucosal lining and produce mild symptoms or sometimes critical clinical diseases with a high risk of mortality, particularly among the immunocompromised. The most common causes of infectious esophagitis are: herpes virus, candida, cytomegalovirus (CMV), and human immunodeficiency virus (HIV); human papilloma virus (HPV) infections are rare in Western countries. Endoscopic features of infectious esophagitis are specific for different agents; nonetheless, differential diagnosis is difficult and requires biopsy, cultures and brushing. We present the clinical case of a young woman admitted to the Department of General Surgery of A.O.U. Federico II, Naples, for a large, deep ulcerative lesion of the esophagus caused by HPV infection.
食管感染可能由多种病原体引起,这些病原体可改变黏膜内衬,导致轻微症状,有时还会引发具有高死亡风险的严重临床疾病,在免疫功能低下者中尤为如此。感染性食管炎最常见的病因包括:疱疹病毒、念珠菌、巨细胞病毒(CMV)和人类免疫缺陷病毒(HIV);人乳头瘤病毒(HPV)感染在西方国家较为罕见。感染性食管炎的内镜特征因病原体不同而具有特异性;尽管如此,鉴别诊断仍很困难,需要进行活检、培养和刷检。我们报告了一名年轻女性的临床病例,该患者因HPV感染导致食管出现巨大、深部溃疡性病变,入住那不勒斯费德里科二世大学综合外科。