Liu Shao, Yi Lun-Zhao, Liang Yi-Zeng
College of Chemistry and Chemical Engineering, Research Center of Modernization of Chinese Medicines, Central South University, Changsha, PR China.
J Sep Sci. 2008 Jun;31(11):2113-37. doi: 10.1002/jssc.200800134.
Traditional Chinese medicines (TCMs) are getting more and more popular nowadays in the whole world for improving health condition of human beings as well as preventing and healing diseases. TCM is a multi-component system with components mostly unknown, and only a few compounds are responsible for the pharmaceutical and/or toxic effects. The large numbers of other components in the TCM make the screening and analysis of the bioactive components extremely difficult. So, separation and analysis of the desired chemical components in TCM are very important subjects for modernization research of TCM. Thus, many novel separation techniques with significant advantages over conventional methods were introduced and applied to separation and analysis of the chemical constituents in TCM. This review presents just a brief outline of the applications of different separation methods for the isolation and analysis of TCM constituents.
如今，传统中药在全世界越来越受欢迎，因为它能改善人类健康状况以及预防和治疗疾病。中药是一个多成分系统，其中大部分成分未知，只有少数化合物具有药理和/或毒性作用。中药中大量的其他成分使得生物活性成分的筛选和分析极其困难。因此，中药中目标化学成分的分离与分析是中药现代化研究的重要课题。于是，许多具有明显优于传统方法优势的新型分离技术被引入并应用于中药化学成分的分离与分析。本综述仅简要概述了不同分离方法在中药成分分离与分析中的应用。
