Liang Xin-miao, Jin Yu, Wang Yan-ping, Jin Gao-wa, Fu Qing, Xiao Yuan-sheng
Dalian Institute of Chemical Physics, Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China.
J Chromatogr A. 2009 Mar 13;1216(11):2033-44. doi: 10.1016/j.chroma.2008.07.026. Epub 2008 Jul 12.
Separation techniques with high efficiency and sensitive detection have been widely used for quality control of traditional Chinese medicines (TCMs). High-performance liquid chromatography, gas chromatography, and capillary electrophoresis are commonly used to separate various components in TCMs. Ultraviolet detection, fluorescence detection, evaporative light-scattering detection, mass spectrometry and nuclear magnetic resonance can be applied to separation techniques for qualitative and quantitative analysis of TCMs. The development of quality control for TCMs based on quantitative and qualitative analysis from 2000 to 2007 are reviewed; the fingerprint technique is also discussed due to its broad application in the quality control of TCMs. Prospects for further research based on our primary results are also discussed.
高效且灵敏检测的分离技术已广泛应用于中药质量控制。高效液相色谱法、气相色谱法和毛细管电泳法常用于分离中药中的各种成分。紫外检测、荧光检测、蒸发光散射检测、质谱和核磁共振可应用于分离技术，用于中药的定性和定量分析。本文综述了2000年至2007年基于定量和定性分析的中药质量控制发展情况；由于指纹图谱技术在中药质量控制中的广泛应用，也对其进行了讨论。还基于我们的初步结果讨论了进一步研究的前景。
