Ramos Sonia, Moulay Leila, Granado-Serrano Ana Belén, Vilanova Olga, Muguerza Begoña, Goya Luis, Bravo Laura
Department of Metabolism and Nutrition, Instituto del Frio, Spanish Council for Scientific Research (CSIC), C/ Jose Antonio Novais 10, 28040 Madrid, Spain.
J Agric Food Chem. 2008 Aug 27;56(16):6985-93. doi: 10.1021/jf8009816. Epub 2008 Jul 12.
A new soluble cocoa fiber product (SCFP), obtained after enzymatic treatment of cocoa husks, was characterized and its potential health effects studied in an animal model of dietary-induced hypercholesterolemia. The SCFP was rich in soluble dietary fiber (DF) and antioxidant polyphenols. Consumption of a cholesterol-rich diet containing the SCFP as a source of DF resulted in lower food intake and body weight gain in comparison with control groups consuming cholesterol-free or cholesterol-rich diets with cellulose as DF. The cholesterol-rich diet caused remarkable hypercholesterolemia. However, the SCFP diminished the negative impact of the cholesterol-rich diet, buffering the decrease of high density lipoprotein-cholesterol, and the increase of total and low density lipoprotein-cholesterol levels, and lipid peroxidation (malondialdehyde levels) induced by the fatty diet. The SCFP also decreased triglyceride levels to values lower than those in the group fed the cholesterol-free diet. These results put forward the potential application of the SCFP as a dietary supplement or functional food ingredient.
一种新的可溶性可可纤维产品(SCFP),是在对可可豆壳进行酶处理后获得的,对其进行了表征,并在饮食诱导的高胆固醇血症动物模型中研究了其潜在的健康影响。SCFP富含可溶性膳食纤维(DF)和抗氧化多酚。与食用不含胆固醇或富含胆固醇且以纤维素作为DF的对照组相比,食用含有SCFP作为DF来源的富含胆固醇的饮食导致食物摄入量和体重增加减少。富含胆固醇的饮食导致显著的高胆固醇血症。然而,SCFP减轻了富含胆固醇饮食的负面影响,缓冲了高密度脂蛋白胆固醇的降低以及高脂肪饮食诱导的总胆固醇和低密度脂蛋白胆固醇水平的升高以及脂质过氧化(丙二醛水平)。SCFP还将甘油三酯水平降低至低于喂食不含胆固醇饮食组的值。这些结果提出了SCFP作为膳食补充剂或功能性食品成分的潜在应用。