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在皮肤科专科诊所和普通诊所对痤疮、银屑病和特应性皮炎患者心理疾病的横断面研究。

A cross-sectional study of psychological morbidity in patients with acne, psoriasis and atopic dermatitis in specialist dermatology and general practices.

作者信息

Magin P J, Pond C D, Smith W T, Watson A B, Goode S M

机构信息

Discipline of General Practice, University of Newcastle, Callaghan, NSW, Australia.

出版信息

J Eur Acad Dermatol Venereol. 2008 Dec;22(12):1435-44. doi: 10.1111/j.1468-3083.2008.02890.x. Epub 2008 Jun 26.

Abstract

BACKGROUND

There is considerable evidence for an association of skin diseases with psychological morbidity. This relationship is best established for acne, psoriasis and atopic eczema. Previous studies have mostly been performed in specialist dermatological practice, and there is a lack of studies that include patients from general practice and a lack of controlled studies employing multivariate analysis.

AIMS/OBJECTIVES: This study aims to examine the relationship of acne, psoriasis and atopic eczema with psychological morbidities in patients recruited from general practice as well as specialist dermatology practice.

METHODS AND SUBJECTS

In this cross-sectional study, 108 patients from general and specialist dermatology practices with the three diseases had disease severity assessed and completed measures of minor psychological disturbance (General Health Questionnaire-12), anxiety and depression (Hospital Anxiety and Depression Scale), public self-consciousness and social anxiety (Fenigstein Self-Consciousness Scale), and neuroticism and extraversion/introversion (Eysenck Personality Inventory). Demographic data were also collected, along with self-ratings of disease severity. Control subjects were 96 patients without skin disease recruited from the same general practices as the subjects.

RESULTS

On univariate analyses, patients with skin disease had higher levels of minor psychological disturbance, public self-consciousness and neuroticism than did controls. There were no differences in psychological measures between specialist and general practice patients or between patients with different skin diseases. On multivariate analyses, the significant differences did not persist.

CONCLUSIONS

This study demonstrates confounding in the relationship of skin diseases with psychological morbidity. The complex relationship of skin disease and psychological morbidity should be re-examined.

摘要

背景

有大量证据表明皮肤病与心理疾病之间存在关联。这种关系在痤疮、银屑病和特应性皮炎中最为明确。以往的研究大多在皮肤科专科实践中进行,缺乏纳入全科医疗患者的研究,也缺乏采用多变量分析的对照研究。

目的

本研究旨在探讨从全科医疗以及皮肤科专科招募的患者中,痤疮、银屑病和特应性皮炎与心理疾病之间的关系。

方法与研究对象

在这项横断面研究中,来自全科和皮肤科专科的108例患有这三种疾病的患者接受了疾病严重程度评估,并完成了轻度心理障碍(一般健康问卷-12)、焦虑和抑郁(医院焦虑抑郁量表)、公众自我意识和社交焦虑(费尼斯坦自我意识量表)以及神经质和外向性/内向性(艾森克人格问卷)的测量。还收集了人口统计学数据以及患者对疾病严重程度的自我评估。对照对象为从与研究对象相同的全科医疗中招募的96例无皮肤病患者。

结果

单变量分析显示,皮肤病患者的轻度心理障碍、公众自我意识和神经质水平高于对照组。专科和全科医疗患者之间或不同皮肤病患者之间在心理测量方面没有差异。多变量分析显示,这些显著差异不再存在。

结论

本研究表明皮肤病与心理疾病之间的关系存在混杂因素。皮肤病与心理疾病之间的复杂关系应重新审视。

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