Stein Jennifer A, Soldano Anthony C, Latkowski Jo-Ann M
Department of Dermatology, New York University, USA.
Dermatol Online J. 2008 May 15;14(5):15.
A 64-year-old woman presented with 2 years of pruritic and ulcerated nodules and tumors on the trunk and arms. Histopathologic examination showed a diffuse infiltrate that consisted of predominantly small lymphocytes and scattered large atypical multinucleated cells positive for CD30. These findings were consistent with a diagnosis of anaplastic large-cell T-cell lymphoma, which is a CD30+ cutaneous lymphoma. This case highlights the importance of considering both histopathologic and clinical criteria in diagnosing a patient with a CD30+ cutaneous lymphoma.
一名64岁女性，躯干和手臂出现瘙痒性溃疡性结节及肿瘤2年。组织病理学检查显示弥漫性浸润，主要由小淋巴细胞和散在的CD30阳性大的非典型多核细胞组成。这些发现符合间变性大细胞T细胞淋巴瘤的诊断，这是一种CD30阳性皮肤淋巴瘤。该病例强调了在诊断CD30阳性皮肤淋巴瘤患者时考虑组织病理学和临床标准的重要性。
