Mardones Francisco, Marshall Guillermo, Viviani Paola, Villarroel Luis, Burkhalter Barton R, Tapia José-Luis, Cerda Jaime, García-Huidobro Trinidad, Ralph Constanza, Oyarzún Enrique, Mardones-Restat Francisco
Department of Public Health, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
J Health Popul Nutr. 2008 Mar;26(1):54-63.
The study was conducted to determine the combined effect of birthweight and gestational age at birth on neonatal mortality using individually-identified livebirths. Logistic regression was used for studying the interactive effect of birthweight and gestational age on the individual probability of neonatal death. All livebirths from Chile in 2000 were included in a linked file. Odds ratio models for birthweight and gestational age were developed for each sex. The probability of neonatal death by sex was presented using contour plots. The models were statistically significant, and odds ratios were different and non-linear for the effects of birthweight and gestational age. Contour plots of constant neonatal mortality according to birthweight and gestational age were presented; they were similar for each sex. A single graph for both sexes that estimates the survival potential of infants born too early or too small would improve neonatal care in developing countries.
本研究旨在利用个体识别的活产儿确定出生体重和出生时孕周对新生儿死亡率的综合影响。采用逻辑回归研究出生体重和孕周对新生儿个体死亡概率的交互作用。2000年智利的所有活产儿被纳入一个链接文件。针对每种性别建立了出生体重和孕周的比值比模型。使用等高线图展示按性别划分的新生儿死亡概率。模型具有统计学意义,出生体重和孕周的影响的比值比不同且呈非线性。给出了根据出生体重和孕周的恒定新生儿死亡率的等高线图;两性的等高线图相似。一张针对两性估计早产或体重过轻婴儿生存潜力的单一图表将改善发展中国家的新生儿护理。