癌症进展的神经内分泌调节
Neuroendocrine modulation of cancer progression.
作者信息
Armaiz-Pena Guillermo N, Lutgendorf Susan K, Cole Steve W, Sood Anil K
机构信息
Department of Gynecologic Oncology, University of Texas, M.D. Anderson Cancer Center, 1155 Herman Pressler, Unit 1362, Houston, TX 77030, USA.
出版信息
Brain Behav Immun. 2009 Jan;23(1):10-5. doi: 10.1016/j.bbi.2008.06.007. Epub 2008 Jun 27.
Abstract
Clinical and animal studies now support the notion that psychological factors such as stress, chronic depression, and lack of social support might promote tumor growth and progression. Recently, cellular and molecular studies have started to identify biological processes that could mediate such effects. This review provides a mechanistic understanding of the relationship between biological and behavioral influences in cancer and points to more comprehensive behavioral and pharmacological approaches for better patient outcomes.
摘要
临床和动物研究现在支持这样一种观点，即压力、慢性抑郁和缺乏社会支持等心理因素可能促进肿瘤的生长和进展。最近，细胞和分子研究已开始确定可能介导此类效应的生物学过程。本综述提供了对癌症中生物学和行为影响之间关系的机制性理解，并指出了采用更全面的行为和药理学方法以实现更好的患者预后。
相似文献
1
Neuroendocrine modulation of cancer progression.癌症进展的神经内分泌调节
Brain Behav Immun. 2009 Jan;23(1):10-5. doi: 10.1016/j.bbi.2008.06.007. Epub 2008 Jun 27.
2
Psychoneuroendocrinology and psychoneuroimmunology of cancer: Plausible mechanisms worth pursuing?癌症的心理神经内分泌学与心理神经免疫学：值得探究的合理机制？
Brain Behav Immun. 2003 Feb;17 Suppl 1:S84-91. doi: 10.1016/s0889-1591(02)00074-0.
3
Neuroimmune and neuroendocrine abnormalities in depression: two sides of the same coin.抑郁症中的神经免疫和神经内分泌异常：同一硬币的两面。
Ann N Y Acad Sci. 2015 Sep;1351:68-79. doi: 10.1111/nyas.12781. Epub 2015 May 5.
4
Stress, Anxiety, and Immunomodulation: A Pharmacological Analysis.压力、焦虑与免疫调节：药理学分析
Vitam Horm. 2017;103:1-25. doi: 10.1016/bs.vh.2016.09.007. Epub 2016 Oct 31.
5
Psychoneuroimmunology and cancer: historical perspectives and current research.心理神经免疫学与癌症：历史视角与当前研究
Adv Neuroimmunol. 1996;6(2):179-90. doi: 10.1016/0960-5428(96)00016-2.
6
Relationship between cancer and psychology: an updated history.癌症与心理学的关系：最新历史。
J Biol Regul Homeost Agents. 2011 Jul-Sep;25(3):331-9.
7
Intersections Between Neuroimmune and Microbiota.神经免疫与微生物群之间的交叉点
Methods Mol Biol. 2018;1781:21-35. doi: 10.1007/978-1-4939-7828-1_2.
8
Surgery, pain, and immune function.手术、疼痛与免疫功能。
CRNA. 1999 Aug;10(3):94-100.
9
Psychobiological responses to social threat: evolution of a psychological model in psychoneuroimmunology.对社会威胁的心理生物学反应：心理神经免疫学中心理模型的演变
Brain Behav Immun. 2009 Jan;23(1):1-9. doi: 10.1016/j.bbi.2008.08.008. Epub 2008 Sep 10.
10
Impact of stress on cancer metastasis.压力对癌症转移的影响。
Future Oncol. 2010 Dec;6(12):1863-81. doi: 10.2217/fon.10.142.
引用本文的文献
1
A Society-to-Cells approach to evaluating multilevel and interrelated drivers of breast cancer disparities in Black women.一种从社会层面到细胞层面的方法，用于评估黑人女性乳腺癌差异的多层次和相互关联的驱动因素。
NPJ Breast Cancer. 2025 Aug 13;11(1):90. doi: 10.1038/s41523-025-00812-0.
2
Applying Neural Networks to Analyse Inflammatory, Sociodemographic, and Psychological Factors in Non-Melanoma Skin Cancer and Colon Cancer: A Statistical and Artificial Intelligence Approach.应用神经网络分析非黑色素瘤皮肤癌和结肠癌中的炎症、社会人口统计学及心理因素：一种统计与人工智能方法
Diagnostics (Basel). 2024 Dec 7;14(23):2759. doi: 10.3390/diagnostics14232759.
3
The β-Adrenergic Receptor: Structure, Physiopathology of Disease, and Emerging Therapeutic Potential.β-肾上腺素能受体：结构、疾病的病理生理学及新兴治疗潜力
Adv Pharmacol Pharm Sci. 2024 Nov 28;2024:2005589. doi: 10.1155/2024/2005589. eCollection 2024.
4
Systemic immunostimulation induces glucocorticoid-mediated thymic involution succeeded by rebound hyperplasia which is impaired in aged recipients.系统性免疫刺激诱导糖皮质激素介导的胸腺萎缩，随后出现反弹性增生，但在老年受者中受损。
Front Immunol. 2024 Sep 9;15:1429912. doi: 10.3389/fimmu.2024.1429912. eCollection 2024.
5
Mechanisms of stress-attributed breast cancer incidence and progression.压力导致乳腺癌发病和进展的机制。
Cancer Causes Control. 2024 Nov;35(11):1413-1432. doi: 10.1007/s10552-024-01884-2. Epub 2024 Jul 16.
6
Caregiver burden and risk of epithelial ovarian cancer in the Nurses' Health Studies.护士健康研究中照顾者负担与上皮性卵巢癌风险
Am J Epidemiol. 2025 Feb 5;194(2):362-369. doi: 10.1093/aje/kwae185.
7
Inequities in the Impacts of Hurricanes and Other Extreme Weather Events for Cancer Survivors.癌症幸存者在飓风和其他极端天气事件影响方面的不公平现象。
Cancer Epidemiol Biomarkers Prev. 2024 Jun 3;33(6):771-778. doi: 10.1158/1055-9965.EPI-23-1029.
8
Psychosocial interventions reduce cortisol in breast cancer patients: systematic review and meta-analysis.心理社会干预可降低乳腺癌患者的皮质醇水平：系统评价与荟萃分析。
Front Psychol. 2023 Jun 27;14:1148805. doi: 10.3389/fpsyg.2023.1148805. eCollection 2023.
9
Chronic stress promotes colorectal cancer progression by enhancing glycolysis through β2-AR/CREB1 signal pathway.慢性应激通过β2-AR/CREB1 信号通路增强糖酵解促进结直肠癌进展。
Int J Biol Sci. 2023 Apr 2;19(7):2006-2019. doi: 10.7150/ijbs.79583. eCollection 2023.
10
The tumor-nerve circuit in breast cancer.乳腺癌的肿瘤-神经回路。
Cancer Metastasis Rev. 2023 Jun;42(2):543-574. doi: 10.1007/s10555-023-10095-1. Epub 2023 Mar 31.
本文引用的文献
1
Personality factors and breast cancer risk: a 13-year follow-up.人格因素与乳腺癌风险：13年随访研究
J Natl Cancer Inst. 2008 Feb 6;100(3):213-8. doi: 10.1093/jnci/djm280. Epub 2008 Jan 29.
2
Neuroendocrine influences on cancer biology.神经内分泌对癌症生物学的影响。
Semin Cancer Biol. 2008 Jun;18(3):164-70. doi: 10.1016/j.semcancer.2007.12.005. Epub 2007 Dec 8.
3
VEGF is differentially regulated in multiple myeloma-derived cell lines by norepinephrine.在多发性骨髓瘤衍生的细胞系中，血管内皮生长因子（VEGF）受去甲肾上腺素的调控存在差异。
Brain Behav Immun. 2008 Mar;22(3):318-23. doi: 10.1016/j.bbi.2007.09.010. Epub 2007 Nov 5.
4
Neuroendocrine modulation of signal transducer and activator of transcription-3 in ovarian cancer.神经内分泌对卵巢癌中信号转导及转录激活因子3的调节作用
Cancer Res. 2007 Nov 1;67(21):10389-96. doi: 10.1158/0008-5472.CAN-07-0858.
5
Stress hormones regulate interleukin-6 expression by human ovarian carcinoma cells through a Src-dependent mechanism.应激激素通过一种依赖Src的机制调节人卵巢癌细胞中白细胞介素-6的表达。
J Biol Chem. 2007 Oct 12;282(41):29919-26. doi: 10.1074/jbc.M611539200. Epub 2007 Aug 23.
6
Tumor cell-organ microenvironment interactions in the pathogenesis of cancer metastasis.肿瘤转移发病机制中的肿瘤细胞与器官微环境相互作用
Endocr Rev. 2007 May;28(3):297-321. doi: 10.1210/er.2006-0027. Epub 2007 Apr 4.
7
Epinephrine protects cancer cells from apoptosis via activation of cAMP-dependent protein kinase and BAD phosphorylation.肾上腺素通过激活环磷酸腺苷（cAMP）依赖性蛋白激酶和BAD磷酸化来保护癌细胞免于凋亡。
J Biol Chem. 2007 May 11;282(19):14094-100. doi: 10.1074/jbc.M611370200. Epub 2007 Mar 12.
8
A chemical biology approach identifies a beta-2 adrenergic receptor agonist that causes human tumor regression by blocking the Raf-1/Mek-1/Erk1/2 pathway.一种化学生物学方法鉴定出一种β-2肾上腺素能受体激动剂，该激动剂通过阻断Raf-1/Mek-1/Erk1/2信号通路导致人类肿瘤消退。
Oncogene. 2007 May 31;26(26):3777-88. doi: 10.1038/sj.onc.1210172. Epub 2007 Jan 29.
9
Modelling molecular mechanisms of breast cancer and invasion: lessons from the normal gland.乳腺癌及侵袭的分子机制建模：来自正常乳腺组织的启示
Biochem Soc Trans. 2007 Feb;35(Pt 1):18-22. doi: 10.1042/BST0350018.
10
Dopaminergic and adrenergic toxicities on SK-N-MC human neuroblastoma cells are mediated through G protein signaling and oxidative stress.多巴胺能和肾上腺素能对SK-N-MC人神经母细胞瘤细胞的毒性是通过G蛋白信号传导和氧化应激介导的。
Apoptosis. 2007 Jan;12(1):167-79. doi: 10.1007/s10495-006-0524-8.
Zotero 插件