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The co-carcinogenic activity of 4-nitropyridine-1-oxide (4-NPO) and prevention of transformation by type-specific anti-viral antibodies.

作者信息

Price P J, Auletta A E, King M P, Hugunin P M, Huebner R J

出版信息

In Vitro. 1976 Aug;12(8):595-8. doi: 10.1007/BF02797444.

DOI:10.1007/BF02797444
PMID:186397
Abstract

Fischer rat embryo cells chronically infected with Rauscher murine leukemia virus, and known to be sensitive to transformation by potent chemical carcinogens, were transformed by the weak carcinogen 4-nitropyridine-1-oxide. Transformed cells grew in semi-solid agar and produced tumors in newborn Fischer rats. Transformation was inhibited by antisera specific for the ecotropic Rauscher murine leukemia virus, but not by antisera of equal toxicity specific for xenotropic Swiss mouse AT-124 virus.

摘要

相似文献

1
The co-carcinogenic activity of 4-nitropyridine-1-oxide (4-NPO) and prevention of transformation by type-specific anti-viral antibodies.
In Vitro. 1976 Aug;12(8):595-8. doi: 10.1007/BF02797444.
2
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Carcinogenicity and mutagenicity of 4-nitropyridine 1-oxide derivatives.4-硝基吡啶1-氧化物衍生物的致癌性和致突变性
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本文引用的文献

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The measurement of proliferation in tissue cultures by enumeration of cell nuclei.通过细胞核计数来测量组织培养中的细胞增殖。
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Carcinogenic action of 4-nitroquinoline-N-oxide.4-硝基喹啉-N-氧化物的致癌作用。
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Hycanthone: a frameshift mutagen.海蒽酮：一种移码诱变剂。
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DNA repair synthesis in mammalian cells exposed to a series of oncogenic and non-oncogenic derivatives of 4-nitroquinoline 1-oxide.暴露于4-硝基喹啉1-氧化物的一系列致癌和非致癌衍生物的哺乳动物细胞中的DNA修复合成。
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On the association between lysogeny and carcinogenicity in nitroquinolines and related compounds.关于硝基喹啉及相关化合物中溶原性与致癌性之间的关联
Experientia. 1968 Dec 15;24(12):1245-8. doi: 10.1007/BF02146650.
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Sensitivity of repair-deficient mutants and similar mutants to 4-nitroquinoline 1-oxide, 4-nitropyridine 1-oxide, and their derivatives.
Cancer Res. 1972 Nov;32(11):2369-74.
8
5-Bromo-2'-deoxyuridine potentiation of transformation of rat-embryo cells induced in vitro by 3-methylcholanthrene: induction of rat leukemia virus gs antigen in transformed cells.
Proc Natl Acad Sci U S A. 1973 Aug;70(8):2415-9. doi: 10.1073/pnas.70.8.2415.
9
Prevention of viral-chemical co-carcinogenesis in vitro by type-specific anti-viral antibody.
Proc Natl Acad Sci U S A. 1976 Jan;73(1):152-5. doi: 10.1073/pnas.73.1.152.
10
I. In vitrol transformation of rat embryo cells: correlations with the known tumorigenic activities of chemicals in rodents.一、大鼠胚胎细胞的体外转化：与啮齿动物中化学物质已知致癌活性的相关性
In Vitro. 1975 Mar-Apr;11(2):107-16. doi: 10.1007/BF02624083.