Ikeda N, Ishii T, Iida S, Kawai T
Second Department of Oral and Maxillofacial Surgery, School of Dentistry, Aichigakuin University, Nagoya, Japan.
Community Dent Oral Epidemiol. 1991 Jun;19(3):160-3. doi: 10.1111/j.1600-0528.1991.tb00133.x.
The purpose of this study was 1) to show the epidemiological status of oral leukoplakia in a selected population of 3131 Japanese (504 women, 2627 men, aged 18-63 yr, mean age 35.9 yr), and 2) to estimate of the validity of the diagnosis of oral leukoplakia by general practitioners. Seventy-seven individuals were detected as having leukoplakia, a prevalence of 2.5%; 2.7% and 1.0% for men and women, respectively, a difference that is statistically significant (P less than 0.001). The percentage of smokers was 75.3% for patients with leukoplakia and 47.8% for individuals detected as not having leukoplakia, a difference which is statistically significant (P less than 0.001). Of 77 leukoplakia patients, 37 cases (48.1%) received a clinically confirmed diagnosis and 27 patients were diagnosed in further examination as having leukoplakia. These results can also be expressed by a positive predictive value of 0.73 and a false positive ratio of 0.27 for the diagnosis of leukoplakia in the primary mass screening by general practitioners. The results of this study suggest that in order to carry out an efficient oral health program in Japan, the objects for mass screening for leukoplakia might be better limited to men over 30 and women over 40 yr of age.
1）展示在3131名日本人（504名女性，2627名男性，年龄在18 - 63岁，平均年龄35.9岁）的特定人群中口腔白斑的流行病学状况；2）评估全科医生对口腔白斑诊断的有效性。77人被检测出患有白斑，患病率为2.5%；男性患病率为2.7%，女性为1.0%，差异具有统计学意义（P < 0.001）。白斑患者中吸烟者的比例为75.3%，未检测出白斑者中吸烟者的比例为47.8%，差异具有统计学意义（P < 0.001）。在77名白斑患者中，37例（48.1%）获得临床确诊，27例患者在进一步检查后被诊断为患有白斑。这些结果也可以通过全科医生在初次大规模筛查中诊断白斑的阳性预测值为0.73和假阳性率为0.27来表示。本研究结果表明，为了在日本开展有效的口腔健康项目，白斑大规模筛查的对象可能最好限定为30岁以上男性和40岁以上女性。
