来自鸟类发生高致病性禽流感地区的猫中甲型H5N1流感病毒的流行情况
Prevalence of influenza A H5N1 virus in cats from areas with occurrence of highly pathogenic avian influenza in birds.
作者信息
Marschall Julia, Schulz Bianka, Harder Priv-Doz Timm C, Vahlenkamp Priv-Doz Thomas W, Huebner Janine, Huisinga Elke, Hartmann Katrin
机构信息
Clinic of Small Animal Medicine, Ludwig Maximilian University, Veterinaerstrasse 13, 80539 Munich, Germany.
出版信息
J Feline Med Surg. 2008 Aug;10(4):355-8. doi: 10.1016/j.jfms.2008.03.007. Epub 2008 Jul 21.
Natural and experimental infections have shown that cats are susceptible to highly pathogenic avian influenza A virus subtype H5N1 (HPAIV H5N1). Cats can be severely affected and die from the disease, but subclinical infections have also been reported. To learn more about the role of cats in the spread of the virus and about the risk posed to cats, the prevalence of H5N1 virus was examined in 171 cats from areas in Germany and Austria in which birds infected with HPAIV H5N1 had been found. Pharyngeal swabs were examined for H5N1 virus using real-time polymerase chain reaction, and serum samples were tested for antibodies to influenza virus. None of the cats showed evidence of infection with H5N1 virus. Prevalence of H5N1 virus was determined to be <1.8% (95% confidence interval (CI): 0.000000-0.017366); prevalence of antibodies was <2.6% (95% CI: 0.000000-0.025068).
自然感染和实验感染均表明，猫对高致病性甲型H5N1禽流感病毒（HPAIV H5N1）易感。猫可能会受到严重影响并死于该疾病，但也有亚临床感染的报道。为了进一步了解猫在病毒传播中的作用以及猫所面临的风险，对德国和奥地利发现感染HPAIV H5N1鸟类的地区的171只猫进行了H5N1病毒流行率检测。使用实时聚合酶链反应检测咽拭子中的H5N1病毒，并检测血清样本中的流感病毒抗体。所有猫均未显示感染H5N1病毒的迹象。H5N1病毒流行率确定为<1.8%（95%置信区间（CI）：0.000000 - 0.017366）；抗体流行率<2.6%（95%CI：0.000000 - 0.025068）。
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