中国东部地区流浪猫中 H5N1 禽流感病毒的检出率。
Detection prevalence of H5N1 avian influenza virus among stray cats in eastern China.
机构信息
State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, People's Republic of China.
Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, People's Republic of China.
出版信息
J Med Virol. 2015 Aug;87(8):1436-40. doi: 10.1002/jmv.24216. Epub 2015 May 7.
Since 1997, more and more cases of the infectious H5N1 avian influenza virus (AIV) in humans have been reported all over the world but the transmission of H5N1 avian influenza virus to stray cats has been little demonstrated. The objective of this pilot investigation was to determine the prevalence of H5N1 AIV antibodies in stray cats in eastern China where is the dominant enzootic H5N1 highly pathogenic avian influenza virus (HP AIV). A total of 1,020 nasal swab and 1,020 serum samples were collected and tested. Evidence of HPAI H5N1 virus antibodies was present in two of the 1,020 serum samples that were positive by HI assay and NT assay, respectively. The results imply little transmission and that the Clade 2.3.2 HPAIV H5N1 infections in poultry did not significantly affect the rural animal shelters or suburban environment in eastern China. In future studies, these results can be used as baseline seroepidemiological levels for H5N1 AIV among cats in China.
自 1997 年以来，全世界范围内报告了越来越多的人类感染 H5N1 禽流感病毒（AIV）的病例，但 H5N1 禽流感病毒向流浪猫的传播却鲜有证明。本初步调查的目的是确定中国东部（H5N1 高致病性禽流感病毒（HP AIV）流行的主要地区）流浪猫中 H5N1 AIV 抗体的流行率。共采集并检测了 1020 份鼻拭子和 1020 份血清样本。HI 检测和 NT 检测均呈阳性的 1020 份血清样本中，有两份样本存在 HPAI H5N1 病毒抗体。结果表明传播很少，禽类中 2.3.2 分支的 HPAIV H5N1 感染并未显著影响中国东部的农村动物收容所或郊区环境。在未来的研究中，这些结果可以作为中国猫中 H5N1 AIV 的基线血清流行病学水平。
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