综述：成瘾的循证治疗
Review. Evidence-based treatments of addiction.
作者信息
O'Brien Charles P
机构信息
Department of Psychiatry, University of Pennsylvania, 3900 Chestnut Street, Philadelphia, PA 19104-6178, USA.
出版信息
Philos Trans R Soc Lond B Biol Sci. 2008 Oct 12;363(1507):3277-86. doi: 10.1098/rstb.2008.0105.
Abstract
Both pharmacotherapy and behavioural treatment are required to relieve the symptoms of addictive disorders. This paper reviews the evidence for the benefits of pharmacotherapy and discusses mechanisms where possible. Animal models of addiction have led to some medications that are effective in reducing symptoms and improving function but they do not produce a cure. Addiction is a chronic disease that tends to recur when treatment is stopped; thus, long-term treatment is recommended.
摘要
药物治疗和行为治疗都需要用于缓解成瘾性障碍的症状。本文回顾了药物治疗益处的证据，并尽可能讨论其作用机制。成瘾的动物模型已催生出一些有效减轻症状和改善功能的药物，但它们无法治愈成瘾。成瘾是一种慢性疾病，在治疗停止时往往会复发；因此，建议进行长期治疗。
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