Aregawi Dawit G, Sherman Jonathan H, Douvas Michael G, Burns Ted M, Schiff David
Department of Neurology, University of Virginia, Charlottesville, Virginia, USA.
Muscle Nerve. 2008 Sep;38(3):1196-200. doi: 10.1002/mus.21089.
We describe a patient in remission from acute lymphoblastic leukemia who developed a painless common peroneal neuropathy. Magnetic resonance imaging (MRI) revealed nerve thickening and enhancement, while a positron emission tomography (PET) scan demonstrated increased fluorodeoxyglucose uptake in a large segment of the neurovascular bundle, suggesting peripheral nerve infiltration. Both findings resolved following treatment with chemotherapy that crossed the blood-nerve barrier. In selected patients presenting with peripheral neuropathy, MRI and PET scan can be helpful in the diagnosis of peripheral nerve infiltration.
我们描述了一名急性淋巴细胞白血病缓解期患者，该患者出现了无痛性腓总神经病变。磁共振成像（MRI）显示神经增粗和强化，而正电子发射断层扫描（PET）显示神经血管束的一大段区域氟脱氧葡萄糖摄取增加，提示周围神经浸润。在接受能穿过血神经屏障的化疗后，这两项检查结果均消失。对于出现周围神经病变的特定患者，MRI和PET扫描有助于诊断周围神经浸润。
