Voin Vlad, Khalid Shehzad, Shrager Sebastian, Tubbs R Shane, Greiner Robert, Thamburaj Krishnamoorthy, Rizk Elias
Research Fellow, Seattle Science Foundation.
Department of Anatomical Sciences, St. George's University School of Medicine, Grenada, West Indies.
Cureus. 2017 Jul 31;9(7):e1529. doi: 10.7759/cureus.1529.
Extramedullary tumors composed of myeloblasts or monoblasts can present in various locations. Patients with a history of acute myeloid leukemia (AML) can present with neuropathic pain and no evidence of relapse of their leukemia. Neuroleukemiosis is a form of extramedullary tumor present in the peripheral nervous systems (PNS) of leukemia patients. We report two AML patients who were in remission and later presented with neurological symptoms due to neuroleukemiosis with negative bone marrow biopsies.
由成髓细胞或原单核细胞组成的髓外肿瘤可出现在不同部位。有急性髓系白血病（AML）病史的患者可能出现神经性疼痛且无白血病复发迹象。神经白血病是白血病患者外周神经系统（PNS）中出现的一种髓外肿瘤形式。我们报告了两名处于缓解期的AML患者，他们后来因神经白血病出现神经症状，骨髓活检结果为阴性。
