Harper Diane M, Paavonen Jorma
Dartmouth College, Department of Women's and Gender Studies, Obstetrics and Gynecology, Community and Family Medicine, Hanover, NH, USA.
Vaccine. 2008 Mar 14;26 Suppl 1:A7-11. doi: 10.1016/j.vaccine.2008.01.013.
HPV vaccination of pre-pubescent girls will be effective for many girls. Vaccinating girls and women older than 12 years of age may accelerate the reduction in cervical cancer rates. Currently HPV vaccines are effective for at least 5 years in the prevention of HPV 16 and 18 associated precancerous lesions however the duration of vaccine protection is unknown. The need for booster shots must therefore be addressed with patients as unknown. Continued cervical cancer screening is necessary regardless of vaccination. Vaccination alone will not eliminate cervical cancer.
对青春期前女孩进行人乳头瘤病毒（HPV）疫苗接种对许多女孩将是有效的。对12岁以上的女孩和妇女进行疫苗接种可能会加速宫颈癌发病率的降低。目前，HPV疫苗在预防HPV 16和18相关癌前病变方面至少5年有效，然而疫苗保护的持续时间尚不清楚。因此，必须向患者说明加强注射的必要性尚不清楚。无论是否接种疫苗，持续进行宫颈癌筛查都是必要的。仅靠接种疫苗并不能消除宫颈癌。
