Tabereaux Paul B, Brass Lawrence M, Concato John, Bravata Dawn M
Richard L. Roudebush VA Medical Center, Indianapolis, IN 46202, USA.
Neuroepidemiology. 2008;31(2):93-9. doi: 10.1159/000146250. Epub 2008 Jul 21.
We sought to describe the proportion of acute ischemic stroke admissions for very old patients (> or =85 years), compare the characteristics of very old versus younger patients and identify factors among very old patients associated with adverse outcomes.
The 2000 Healthcare Cost and Utilization Project data included acute ischemic stroke hospitalizations for patients > or =45 years. The combined outcome was in-hospital mortality or discharge to a long-term care facility.
Among 15,020 stroke hospitalizations, 20.4% were for very old patients. The outcome rate was higher in hospitalizations for very old patients (2,176/3,058, 71.2%; versus 5,748/11,962, 48%; p < 0.0001). More hospitalizations for very old patients were for women (73.5 versus 55.1%; p < 0.0001), fewer for Blacks (6.1 versus 12.3%; p < 0.0001) and fewer at teaching hospitals (30.4 versus 36.2%; p < 0.0001). Among very old patients, factors that were independently associated with the outcome included: age [years; adjusted OR = 1.02 (95% CI = 1.000-1.05)], female gender [1.4 (1.18-1.68)], atrial fibrillation [1.37 (1.15-1.63)], acute myocardial infarction [1.68 (1.20-2.35)], respiratory failure [3.59 (1.60-8.05)] and teaching hospital admission [0.82 (0.69-0.98)]. Similar results were observed in the hospitalizations for younger patients. The adjusted OR for the outcome displayed geographic disparities in both age groups, but the pattern of the geographic variation was not similar between the two age groups.
The very old constitute a substantial proportion of stroke hospitalizations. Hospitalizations for very old patients are more likely to end in death or discharge to a long-term care facility than hospitalizations for younger patients. The pattern of geographic disparity in poststroke adverse outcomes differs between younger and very old patients.
我们试图描述高龄患者(≥85岁)急性缺血性卒中住院患者的比例,比较高龄患者与年轻患者的特征,并确定高龄患者中与不良结局相关的因素。
2000年医疗保健成本与使用项目数据包括≥45岁患者的急性缺血性卒中住院情况。综合结局为住院死亡率或出院至长期护理机构。
在15,020例卒中住院病例中,20.4%为高龄患者。高龄患者住院的结局发生率更高(2,176/3,058,71.2%;相比5,748/11,962,48%;p<0.0001)。高龄患者女性住院比例更高(73.5%对55.1%;p<0.0001),黑人患者住院比例更低(6.1%对12.3%;p<0.0001),教学医院的住院比例更低(30.4%对36.2%;p<0.0001)。在高龄患者中,与结局独立相关的因素包括:年龄[岁;调整后的比值比(OR)=1.02(95%可信区间(CI)=1.000 - 1.05)]、女性性别[1.4(1.18 - 1.68)]、心房颤动[1.37(1.15 - 1.63)]、急性心肌梗死[1.68(1.20 - 2.35)]、呼吸衰竭[3.59(1.60 - 8.05)]和教学医院入院[0.82(0.69 - 0.98)]。年轻患者住院情况也观察到类似结果。结局的调整后OR在两个年龄组中均显示出地理差异,但两个年龄组的地理差异模式并不相似。
高龄患者占卒中住院病例的相当比例。高龄患者住院比年轻患者住院更有可能以死亡或出院至长期护理机构告终。年轻患者和高龄患者卒中后不良结局的地理差异模式不同。