Polshettiwar Vivek, Varma Rajender S
Sustainable Technology Division, National Risk Management Research Laboratory, US Environmental Protection Agency, Cincinnati, Ohio 45268, USA.
Chem Soc Rev. 2008 Aug;37(8):1546-57. doi: 10.1039/b716534j. Epub 2008 Jun 6.
The development of "Greener Organic Chemistry" is due to the recognition that environmentally friendly products and processes will be economical in the long term as they circumvent the need for treating 'end-of-the-pipe' pollutants and by-products generated by conventional synthesis. The fundamentals and significant outcomes of microwave-assisted organic synthesis in aqueous medium are summarized in this tutorial review, which have resulted in the development of relatively sustainable and environmentally benign protocols for the synthesis of drugs and fine chemicals.
“绿色有机化学”的发展源于这样一种认识：从长远来看，环境友好型产品和工艺将具有经济性，因为它们避免了处理传统合成产生的“末端”污染物和副产物的需求。本教程综述总结了水介质中微波辅助有机合成的基本原理和重要成果，这些成果推动了相对可持续且环境友好的药物和精细化学品合成方案的发展。
