Shabanloo Rasool, Montazer Majid, Farahani Ali, Karimi Nesa
Textile Engineering Department, School of Materials and Advanced Processes Engineering, Amirkabir University of Technology (Tehran Polytechnic), Tehran, Iran.
Department of Polymer Engineering and Color Technology, Amirkabir University of Technology, Tehran, Iran.
Heliyon. 2025 Jan 10;11(2):e41863. doi: 10.1016/j.heliyon.2025.e41863. eCollection 2025 Jan 30.
Electrospun nanofibers with a high surface area are attractive materials for biomedical applications. They have potential use in scaffolds, drug delivery, bio face masks, wound dressings, and biosensors. Various surface modifications have been developed to improve their chemical and physical properties. These modifications include physical, chemical, biological, and nano-treatment approaches. The physical modification includes annealing, stretching, and plasma treatment. Chemical modification includes functionalization with chemical groups, while biological modification involves coating with proteins, enzymes, or antibodies. Nanotreatment approaches use nanomaterials to modify the surface of nanofibers. These modifications enhance the characteristics of the biomedical nanofibers, making them more effective and efficient for their intended applications. The review summarizes the latest research on electrospun nanofiber modification procedures, strategies, and utilities for various biomedical applications. It provides insights into the conditions and requirements of each modification approach and their effects on the properties of the nanofibers. Moreover, it emphasizes the importance of functionalizing nanofibers to meet the most important specific requirements and the potential of electrospun nanofibers in various biomedical applications.
具有高表面积的电纺纳米纤维是生物医学应用中具有吸引力的材料。它们在支架、药物递送、生物面罩、伤口敷料和生物传感器方面具有潜在用途。已经开发了各种表面改性方法来改善其化学和物理性质。这些改性包括物理、化学、生物和纳米处理方法。物理改性包括退火、拉伸和等离子体处理。化学改性包括用化学基团进行功能化，而生物改性涉及用蛋白质、酶或抗体进行涂层。纳米处理方法使用纳米材料来修饰纳米纤维的表面。这些改性增强了生物医学纳米纤维的特性，使其在预期应用中更有效率。该综述总结了电纺纳米纤维改性程序、策略以及在各种生物医学应用中的效用的最新研究。它深入探讨了每种改性方法的条件和要求以及它们对纳米纤维性能的影响。此外，它强调了使纳米纤维功能化以满足最重要的特定要求的重要性以及电纺纳米纤维在各种生物医学应用中的潜力。
