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用于计算机辅助骨肿瘤手术的图像融合

Image fusion for computer-assisted bone tumor surgery.

作者信息

Wong Kwok Chuen, Kumta Shekhar Madhuker, Antonio Gregory Ernest, Tse Lung Fung

机构信息

Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong.

出版信息

Clin Orthop Relat Res. 2008 Oct;466(10):2533-41. doi: 10.1007/s11999-008-0374-5. Epub 2008 Jul 22.

Abstract

The fusion of computed tomography and magnetic resonance images is a software-dependent processing technique that enables one to integrate and analyze preoperative images for planning complex musculoskeletal tumor resections. By integrating various imaging modalities into one imaging data set we may facilitate preoperative image analysis and planning of navigation computer-assisted bone tumor resection and reconstruction. We performed image fusion for computer-assisted tumor surgery in 13 consecutive patients, seven males and six females, with a mean age of 35.8 years (range, 6-80 years). Visual verification of fused images was accurate in all patients. The mean time for image fusion was 30.6 minutes (range, 8-80 minutes). After intraoperative registration, all tumor resections were performed as planned preoperatively under navigation image guidance. Resections achieved after navigation resection planning were validated by postoperative CT or resected specimens in seven patients. Histologic examination of all resected specimens showed tumor-free margins in patients with bone sarcoma. The fusion of computed tomography and magnetic resonance imaging has the potential to enhance computer-assisted bone tumor surgery. The fusion image, when combined with surgical navigation, helps surgeons reproduce a preoperative plan reliably and may offer substantial clinical benefits.

摘要

计算机断层扫描(CT)与磁共振成像(MRI)的融合是一种依赖软件的处理技术,它能使人们整合并分析术前图像,以规划复杂的肌肉骨骼肿瘤切除术。通过将各种成像模态整合到一个成像数据集中,我们可以促进术前图像分析以及导航计算机辅助骨肿瘤切除与重建的规划。我们对13例连续患者进行了计算机辅助肿瘤手术的图像融合,其中男性7例,女性6例,平均年龄35.8岁(范围6 - 80岁)。所有患者融合图像的视觉验证均准确无误。图像融合的平均时间为30.6分钟(范围8 - 80分钟)。术中配准后,所有肿瘤切除均在导航图像引导下按术前计划进行。7例患者术后通过CT或切除标本对导航切除规划后实现的切除情况进行了验证。所有切除标本的组织学检查显示骨肉瘤患者切缘无肿瘤。计算机断层扫描与磁共振成像的融合有增强计算机辅助骨肿瘤手术的潜力。融合图像与手术导航相结合,有助于外科医生可靠地重现术前计划,并可能带来显著的临床益处。

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