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躯干复杂骨肿瘤——3D打印与导航在肿瘤骨科中的作用:病例系列及文献综述

Complex Bone Tumors of the Trunk-The Role of 3D Printing and Navigation in Tumor Orthopedics: A Case Series and Review of the Literature.

作者信息

Schulze Martin, Gosheger Georg, Bockholt Sebastian, De Vaal Marieke, Budny Tymo, Tönnemann Max, Pützler Jan, Bövingloh Albert Schulze, Rischen Robert, Hofbauer Vincent, Lübben Timo, Deventer Niklas, Ahrens Helmut

机构信息

Department of Orthopedics and Tumor Orthopedics, Muenster University Hospital, Albert-Schweitzer-Campus 1, 48149 Münster, Germany.

Clinic for Radiology, Muenster University Hospital, Albert-Schweitzer-Campus 1, 48149 Muenster, Germany.

出版信息

J Pers Med. 2021 Jun 4;11(6):517. doi: 10.3390/jpm11060517.

DOI:10.3390/jpm11060517
PMID:34200075
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8228871/
Abstract

The combination of 3D printing and navigation promises improvements in surgical procedures and outcomes for complex bone tumor resection of the trunk, but its features have rarely been described in the literature. Five patients with trunk tumors were surgically treated in our institution using a combination of 3D printing and navigation. The main process includes segmentation, virtual modeling and build preparation, as well as quality assessment. Tumor resection was performed with navigated instruments. Preoperative planning supported clear margin multiplanar resections with intraoperatively adaptable real-time visualization of navigated instruments. The follow-up ranged from 2-15 months with a good functional result. The present results and the review of the current literature reflect the trend and the diverse applications of 3D printing in the medical field. 3D printing at hospital sites is often not standardized, but regulatory aspects may serve as disincentives. However, 3D printing has an increasing impact on precision medicine, and we are convinced that our process represents a valuable contribution in the context of patient-centered individual care.

摘要

3D打印与导航技术相结合有望改善躯干复杂骨肿瘤切除手术的操作过程及结果,但相关文献对其特点鲜有描述。我院采用3D打印与导航技术联合治疗了5例躯干肿瘤患者。主要过程包括分割、虚拟建模与构建准备以及质量评估。使用导航器械进行肿瘤切除。术前规划支持多平面清晰切缘切除,术中可实时直观看到导航器械。随访时间为2至15个月,功能结果良好。目前的结果以及对现有文献的综述反映了3D打印在医学领域的发展趋势和多样应用。医院现场的3D打印往往不规范,但监管方面可能会起到抑制作用。然而,3D打印对精准医学的影响日益增大,我们坚信我们的流程在以患者为中心的个性化医疗背景下具有重要价值。

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Implementation of the three-dimensional printing technology in treatment of bone tumours: a case series.
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