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一名接受精原细胞瘤治疗的男性表型(XY)雌雄同体者,通过体外受精-卵胞浆内单精子注射技术生育了一个健康的孩子。

A male phenotype (XY) hermaphrodite treated for seminoma, fathered a healthy child by IVF-ICSI technique.

作者信息

Zayed Faheem, Ghalayini Ibrahim, Matalka Ismail

机构信息

University Department of Obstetrics and Gynaecology, King Abdullah University Hospital, Jordan University of Science and Technology, Irbid, Jordan.

出版信息

J Assist Reprod Genet. 2008 Jul;25(7):345-8. doi: 10.1007/s10815-008-9234-1. Epub 2008 Jul 22.

Abstract

OBJECTIVE

To report a successful delivery of a healthy infant fathered by an infertile 46, XY true hermaphrodite who suffered from a seminoma.

DESIGN

Case report

SETTING

IVF unit in University hospital.

PATIENT(S): Male 41 years (true hermaphrodite), his wife 35 years.

MAIN OUTCOME MEASURES

Laboratory, pathology tests and ultrasound tests.

RESULTS

The above patient treated and cured from seminoma, the couple had in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) using frozen testicular sperm and had a healthy baby.

CONCLUSION

This is the first case report of a successful delivery of a healthy infant fathered by an infertile 46, XY true hermaphrodite who suffered from a seminoma. Once treated and cured, the couple had IVF and ICSI using frozen testicular sperm and had a healthy baby.

摘要

目的

报告一例由患有精原细胞瘤的46, XY真性两性畸形不育男性成功诞下健康婴儿的病例。

设计

病例报告

地点

大学医院的体外受精科室

患者

男性,41岁(真性两性畸形),其妻子35岁

主要观察指标

实验室检查、病理检查及超声检查

结果

上述患者的精原细胞瘤得到治疗并治愈,这对夫妇使用冷冻的睾丸精子进行了体外受精(IVF)和卵胞浆内单精子注射(ICSI),并诞下一名健康婴儿。

结论

这是首例关于由患有精原细胞瘤的46, XY真性两性畸形不育男性成功诞下健康婴儿的病例报告。一旦接受治疗并治愈,这对夫妇使用冷冻的睾丸精子进行了IVF和ICSI,并诞下一名健康婴儿。

相似文献

1
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本文引用的文献

1
Seminoma in a male phenotype 46XX true hermaphrodite.
Asian J Surg. 2007 Jan;30(1):85-7. doi: 10.1016/S1015-9584(09)60136-6.
2
Testicular sperm extraction in cancerous testicle in patients with azoospermia: a case report.
Hum Reprod. 2007 Apr;22(4):1068-72. doi: 10.1093/humrep/del468. Epub 2006 Dec 15.
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Increased incidence of testicular cancer in men presenting with infertility and abnormal semen analysis.
J Urol. 2005 Nov;174(5):1819-22; discussion 1822. doi: 10.1097/01.ju.0000177491.98461.aa.
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Chromosomal studies of three hermaphrodites.
Am J Med. 1962 Jul;33:83-7. doi: 10.1016/0002-9343(62)90279-6.
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Testicular sperm extraction in a patient with metachronous bilateral testicular cancer.
Hum Reprod. 2001 Nov;16(11):2343-6. doi: 10.1093/humrep/16.11.2343.
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Risk of testicular cancer in subfertile men: case-control study.
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