Stava Charles J, Beck Martha L, Feng Lei, Lopez Adriana, Busaidy Naifa, Vassilopoulou-Sellin Rena
Department of Endocrine Neoplasia and Hormonal Disorders, The University of Texas M.D. Anderson Cancer Center, Box 435, 1515 Holcombe Blvd., Houston, TX 77030, USA.
J Cancer Surviv. 2007 Jun;1(2):108-15. doi: 10.1007/s11764-007-0016-z.
Cancer and cancer treatments are associated with diabetes mellitus in some patients. The purpose of this review is to look at the association and potential impact of diabetes mellitus on the health profiles of a large cohort of cancer survivors.
This is a descriptive, cross-sectional study of long-term cancer survivors who reported that they have diabetes. Of 8,559 respondents to a mailed survey, 696 (8.1%) reported diabetes mellitus (DM). We analyzed the responses to discern the potential impact of demographics, cancer type, or disease treatments on glycemia as well as the potential impact of DM on socioeconomic parameters (education, family and work).
Survivors of gynecological cancer, chronic leukemia, or gastrointestinal cancer reported DM most frequently, although no statistical correlations could be demonstrated for DM and specific cancer types. The frequency of DM was higher among survivors than in the general U.S. population. Cancer survivors with DM were more likely to report that cancer affected their overall health (42.3 vs. 34.3%) and ability to work. They also reported more health problems.
Diabetes mellitus affects a minority of long-term cancer survivors and may have an impact on their physiologic and psychosocial well-being.
Systematic assessment for DM is suggested for all cancer survivors because DM appears to be an important co-morbidity for this growing segment of our population.
在一些患者中，癌症及癌症治疗与糖尿病相关。本综述的目的是研究糖尿病与一大群癌症幸存者健康状况之间的关联及潜在影响。
这是一项对报告患有糖尿病的长期癌症幸存者进行的描述性横断面研究。在对邮寄调查问卷的8559名受访者中，696人（8.1%）报告患有糖尿病（DM）。我们分析这些回答，以辨别人口统计学、癌症类型或疾病治疗对血糖的潜在影响，以及糖尿病对社会经济参数（教育、家庭和工作）的潜在影响。
妇科癌症、慢性白血病或胃肠道癌症的幸存者报告患糖尿病的频率最高，尽管糖尿病与特定癌症类型之间未显示出统计学相关性。幸存者中糖尿病的发生率高于美国普通人群。患有糖尿病的癌症幸存者更有可能报告癌症影响了他们的整体健康（42.3%对34.3%）和工作能力。他们还报告了更多的健康问题。
糖尿病影响少数长期癌症幸存者，可能对他们的生理和心理社会福祉产生影响。
建议对所有癌症幸存者进行糖尿病的系统评估，因为糖尿病似乎是这一不断增长的人群中的一种重要合并症。
