Tea Muy-Kheng M, Grimm Christoph, Fink-Retter Anneliese, Bikas Diana, Kroiss Regina, Kubista Ernst, Wagner Teresa
Department of Obstetrics and Gynecology, Division of Senology, Medical University of Vienna, Vienna, Austria.
Am J Surg. 2009 Feb;197(2):199-202. doi: 10.1016/j.amjsurg.2007.11.028. Epub 2008 Jul 23.
Breast cysts are the most common cause of benign breast masses. Simple breast cysts do not need further evaluation, but complex breast cysts require additional assessment due to the potential presence of malignancy. However, these complex cysts have rarely been examined and quantified according to the associated cancer detection rate. Our study is the first investigation to evaluate the malignancy rate of complex breast cysts identified by histopathological results.
Imaging findings of complex cysts were correlated retrospectively with clinical and pathologic outcomes. We detected a malignancy rate of 14%. Sonographic criteria of a complex cyst such as thick cyst wall (P = .0006), lobulation (P = .01), and hyperechogenicity (P = .04) were predictive of neoplasm. Two or more criteria combined were associated with a 13.6-fold higher risk of malignancy (P <.0001).
Based on our results we reinforce the importance of adequate assessment of complex breast cysts to prevent a missed or delayed diagnosis of malignancy.
乳腺囊肿是乳腺良性肿块最常见的病因。单纯性乳腺囊肿无需进一步评估，但复杂性乳腺囊肿因可能存在恶性病变而需要额外评估。然而，这些复杂性囊肿很少根据相关癌症检出率进行检查和量化。我们的研究是首次根据组织病理学结果评估复杂性乳腺囊肿恶性率的调查。
回顾性分析复杂性囊肿的影像学表现与临床及病理结果的相关性。我们检测到恶性率为14%。复杂性囊肿的超声标准，如囊壁增厚（P = 0.0006）、分叶（P = 0.01）和高回声（P = 0.04）可预测肿瘤。两个或更多标准联合出现与恶性风险高13.6倍相关（P < 0.0001）。
基于我们的结果，我们强调了充分评估复杂性乳腺囊肿以防止漏诊或延误恶性肿瘤诊断的重要性。
