Grosso A, Gardelli G, Mei F, Battista G, Boriani F, Ghigi G, Motta R, Marino S A, Burlizzi S, Corinaldesi A
Istituto di Radiologia, Policlinico S. Orsola, Bologna.
Radiol Med. 1996 Mar;91(3):194-7.
Many studies on the biochemical composition of the liquid aspirated from breast cysts have identified three types of cysts: type I (apocrine) cysts, with a high concentration of K+ and low levels of Na+ and C1-; type II (transudate) cysts, with an electrolytic content similar to that of plasma and high Na+ levels and, finally, type III cysts, with intermediate characteristics. The literature data appear to indicate that the women with type I cysts are at higher risk for breast cancer. The authors report the results of a study carried out on 143 women from October, 1991, through October, 1994, in the Radiology Department of the University of Bologna, to investigate the correlations between some risk factors for breast cancer, the characteristics of cyst fluid and the morphology of the cysts after pneumocystography. Of 186 cysts, 104 (55.9%) were type I, 49 (26.4%) were type II, and 33 (17.7%) were type III. Among the risk factors we considered, only the premenopausal state (41 to 45 years of age) exhibited a statistically significant correlation with the presence of type I cysts. The morphological study of the cysts after pneumocystography showed a surprisingly high correlation between the honeycomb pattern and type I cysts. The constant correlation between cyst morphology and electrolytic content may allow the easy identification of the subgroups of patients eligible for a closer follow-up.
I型（大汗腺）囊肿，钾离子浓度高，钠离子和氯离子水平低；II型（漏出液）囊肿，其电解质成分与血浆相似，钠离子水平高，最后是III型囊肿，具有中间特征。文献数据似乎表明，患有I型囊肿的女性患乳腺癌的风险更高。作者报告了1991年10月至1994年10月在博洛尼亚大学放射科对143名女性进行的一项研究结果，以调查乳腺癌的一些风险因素、囊肿液的特征与充气造影后囊肿形态之间的相关性。在186个囊肿中，104个（55.9%）为I型，49个（26.4%）为II型，33个（17.7%）为III型。在我们考虑的风险因素中，只有绝经前状态（41至45岁）与I型囊肿的存在呈现出统计学上的显著相关性。充气造影后对囊肿的形态学研究表明，蜂窝状模式与I型囊肿之间存在惊人的高度相关性。囊肿形态与电解质成分之间的持续相关性可能有助于轻松识别适合密切随访的患者亚组。
