Allgayer H, Fulda S
Department of Experimental Surgery, Joint Unit Molecular Oncology of Solid Tumors, DKFZ (German Cancer Research Center) Heidelberg, Mannheim Medical Faculty, Ruprecht Karls University Heidelberg, Germany.
Adv Med Sci. 2008;53(2):130-8. doi: 10.2478/v10039-008-0025-9.
The rapidly advancing elucidation of molecular targets in human cancers during the last decade has provided an excellent basis for the development of novel therapeutics. A huge variety of potential target structures have been identified, many of which are already being exploited for therapeutic purposes. This review introduces the reader into the concept of molecular targeted therapies, and provides some prototypic examples.
在过去十年中，对人类癌症分子靶点的快速深入研究为新型疗法的开发提供了良好基础。已鉴定出大量潜在的靶点结构，其中许多已被用于治疗目的。本综述向读者介绍分子靶向治疗的概念，并提供一些典型例子。
