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外科阿普加评分能衡量术中表现吗?

Does the Surgical Apgar Score measure intraoperative performance?

作者信息

Regenbogen Scott E, Lancaster R Todd, Lipsitz Stuart R, Greenberg Caprice C, Hutter Matthew M, Gawande Atul A

机构信息

Department of Health Policy and Management, Harvard School of Public Health, Boston, Massachusetts 02115, USA.

出版信息

Ann Surg. 2008 Aug;248(2):320-8. doi: 10.1097/SLA.0b013e318181c6b1.

Abstract

OBJECTIVE

To evaluate whether Surgical Apgar Scores measure the relationship between intraoperative care and surgical outcomes.

SUMMARY BACKGROUND DATA

With preoperative risk-adjustment now well-developed, the role of intraoperative performance in surgical outcomes may be considered. We previously derived and validated a 10-point Surgical Apgar Score--based on intraoperative blood loss, heart rate, and blood pressure--that effectively predicts major postoperative complications within 30 days of general and vascular surgery. This study evaluates whether the predictive value of this score comes solely from patients' preoperative risk or also measures care in the operating room.

METHODS

Among a systematic sample of 4119 general and vascular surgery patients at a major academic hospital, we constructed a detailed risk-prediction model including 27 patient-comorbidity and procedure-complexity variables, and computed patients' propensity to suffer a major postoperative complication. We evaluated the prognostic value of patients' Surgical Apgar Scores before and after adjustment for this preoperative risk.

RESULTS

After risk-adjustment, the Surgical Apgar Score remained strongly correlated with postoperative outcomes (P < 0.0001). Odds of major complications among average-scoring patients (scores 7-8) were equivalent to preoperative predictions (likelihood ratio (LR) 1.05, 95% CI 0.78-1.41), significantly decreased for those who achieved the best scores of 9-10 (LR 0.52, 95% CI 0.35-0.78), and were significantly poorer for those with low scores--LRs 1.60 (1.12-2.28) for scores 5-6, and 2.80 (1.50-5.21) for scores 0-4.

CONCLUSIONS

Even after accounting for fixed preoperative risk--due to patients' acute condition, comorbidities and/or operative complexity--the Surgical Apgar Score appears to detect differences in intraoperative management that reduce odds of major complications by half or increase them by nearly 3-fold.

摘要

目的

评估手术阿普加评分是否能衡量术中护理与手术结果之间的关系。

总结背景数据

随着术前风险调整现已得到充分发展,术中表现对手术结果的作用值得考虑。我们之前基于术中失血、心率和血压得出并验证了一个10分的手术阿普加评分,该评分能有效预测普通外科和血管外科手术后30天内的主要并发症。本研究评估该评分的预测价值是仅来自患者的术前风险,还是也能衡量手术室护理情况。

方法

在一家大型学术医院的4119例普通外科和血管外科患者的系统样本中,我们构建了一个详细的风险预测模型,包括27个患者合并症和手术复杂性变量,并计算患者发生术后主要并发症的倾向。我们评估了在调整术前风险前后患者手术阿普加评分的预后价值。

结果

风险调整后,手术阿普加评分与术后结果仍密切相关(P < 0.0001)。平均评分患者(评分7 - 8)发生主要并发症的几率与术前预测相当(似然比(LR)1.05,95%置信区间0.78 - 1.41),对于获得9 - 10分最佳评分的患者,几率显著降低(LR 0.52,95%置信区间0.35 - 0.78),而对于低分患者,几率明显更差——评分5 - 6的患者LR为1.60(1.12 - 2.28),评分0 - 4的患者LR为2.80(1.50 - 5.21)。

结论

即使考虑了因患者急性病情、合并症和/或手术复杂性导致的固定术前风险,手术阿普加评分似乎仍能检测出术中管理的差异,这些差异可使主要并发症的几率降低一半或增加近3倍。

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