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单独椎间融合器与颈椎前路钢板治疗颈椎间盘突出症:融合器下沉的连续变化

Stand-alone interbody cage versus anterior cervical plate for treatment of cervical disc herniation: sequential changes in cage subsidence.

作者信息

Fujibayashi Shunsuke, Neo Masashi, Nakamura Takashi

机构信息

Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawaharacho, Sakyo-ku, Kyoto 606-8507, Japan.

出版信息

J Clin Neurosci. 2008 Sep;15(9):1017-22. doi: 10.1016/j.jocn.2007.05.011. Epub 2008 Jul 23.

Abstract

Anterior cervical discectomy and fusion with an autogenous iliac bone graft is the gold standard treatment for cervical disc herniation. However, autologous bone grafts obtained from the anterior iliac crest are associated with significant donor-site morbidity and complications. To decrease bone graft-related problems, several types of interbody fusion cage have been developed and are used widely in clinical practice. We compared the clinical and radiological outcomes for two surgical procedures used to treat cervical disc herniation: the stand-alone interbody cage and autologous iliac bone grafting with an anterior plate. The clinical results did not differ between patients treated with the two procedures. The stand-alone cage was less invasive and had less donor-site morbidity. In patients treated with the bone graft and plate, the alignment of the fused segment was maintained in all but one patient, who exhibited nonunion. In contrast, in the cage-treated group, 44% of patients exhibited loss of lordotic alignment of more than 5 degrees and cage subsidence of 3 mm or more. All cage subsidence occurred within 3 months of surgery. Although the stand-alone cage was a less invasive and more effective procedure to treat cervical disc herniation, surgeons should consider the possible drawbacks of the associated subsidence.

摘要

颈椎前路椎间盘切除及自体髂骨移植融合术是治疗颈椎间盘突出症的金标准术式。然而,取自髂前嵴的自体骨移植会带来明显的供区并发症。为减少与骨移植相关的问题,已研发出多种类型的椎间融合器并在临床实践中广泛应用。我们比较了用于治疗颈椎间盘突出症的两种手术方法的临床和影像学结果:单独使用椎间融合器和自体髂骨移植并前路钢板固定。两种手术治疗的患者临床结果无差异。单独使用融合器的手术创伤较小,供区并发症也较少。在接受骨移植和钢板固定治疗的患者中,除1例出现骨不连外,其余患者融合节段的对线均得以维持。相比之下,在融合器治疗组中,44%的患者出现了超过5度的前凸对线丢失以及3毫米或以上的融合器下沉。所有融合器下沉均发生在术后3个月内。尽管单独使用融合器是一种治疗颈椎间盘突出症的微创且更有效的手术方法,但外科医生应考虑到相关下沉可能带来的缺点。

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