Edwards Jayson D, Bower Kraig S, Sediq Denise A, Burka Jenna M, Stutzman Richard D, Vanroekel Cameron R, Kuzmowych Chrystyna P, Eaddy Jennifer B
Center for Refractive Surgery, Walter Reed Army Medical Center, Washington, DC 20307-5001, USA.
J Cataract Refract Surg. 2008 Aug;34(8):1288-94. doi: 10.1016/j.jcrs.2008.04.024.
To evaluate postoperative healing between bandage contact lenses with high and low oxygen permeability in patients having photorefractive keratectomy (PRK).
Center for Refractive Surgery, Walter Reed Army Medical Center, Washington, DC, USA.
This retrospective study compared patients receiving a high-oxygen-transmission bandage contact lens (Focus Night & Day [N&D], Ciba Vision; n = 92) and those receiving a low-oxygen-transmission lens (Proclear, Cooper Vision; n = 114) after PRK. Visual outcomes, safety, and efficacy were assessed postoperatively at 1, 4, and 7 days and 1, 3, 6, and 12 months.
Overall pain scores were higher in the Proclear group at 1 day (P = .000) and 4 days (P = .027). The N&D group had an increase in corneal infiltrates at 4 days (P = .025) and 1 week (P = .017). At 1 month, 40.4% of patients in the Proclear group and 18.6% in the N&D group had a 1 or more line decrease in best spectacle-corrected visual acuity (BSCVA) (P = .002). Although there was a trend toward a higher haze rate in the Proclear group, it was not statistically significant (P = .064). There was no statistically significant difference in uncorrected visual acuity, goal of emmetropia, contrast sensitivity, or reepithelialization.
The N&D lens produced less pain and better postoperative results in terms of haze and BSCVA at 1 month. However, it led to a higher incidence of corneal infiltrates. There was no difference between the lenses in the end result at 12 months.
评估接受准分子激光原位角膜磨镶术（PRK）的患者使用高透氧性和低透氧性绷带式隐形眼镜后的术后愈合情况。
美国华盛顿特区沃尔特·里德陆军医疗中心屈光手术中心。
这项回顾性研究比较了PRK术后接受高透氧绷带式隐形眼镜（Focus Night & Day [N&D]，博士伦公司；n = 92）和接受低透氧性镜片（Proclear，库博光学公司；n = 114）的患者。在术后1天、4天、7天以及1个月、3个月、6个月和12个月评估视力结果、安全性和有效性。
Proclear组在术后1天（P = 0.000）和4天（P = 0.027）的总体疼痛评分更高。N&D组在术后4天（P = 0.025）和1周（P = 0.017）角膜浸润增加。在术后1个月时，Proclear组40.4%的患者和N&D组18.6%的患者最佳矫正视力（BSCVA）下降了1行或更多行（P = 0.002）。尽管Proclear组的 haze发生率有升高趋势，但差异无统计学意义（P = 0.064）。在未矫正视力、正视化目标、对比敏感度或上皮化方面，两组之间无统计学显著差异。
N&D镜片在术后1个月时疼痛较轻，在haze和BSCVA方面术后效果更好。然而，它导致角膜浸润的发生率更高。在术后12个月时，两种镜片的最终结果无差异。
