Institute of Vision and Optics, Faculty of Medicine, University of Crete, Crete, Greece.
J Cataract Refract Surg. 2009 Dec;35(12):2103-8. doi: 10.1016/j.jcrs.2009.07.015.
To compare the efficacy of 2 types of silicone hydrogel bandage contact lenses with high oxygen transmissibility after photorefractive keratectomy (PRK).
Institute of Vision and Optics, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece.
In this prospective study, 1 eye of patients having bilateral PRK was randomly fitted with a bandage contact lens of lotrafilcon A (Night & Day) and the fellow eye, with a bandage contact lens of lotrafilcon B (O(2)Optix). The patients and the examiner were masked to which bandage contact lens type was in which eye. Patients were examined on the day of surgery and 1, 3, and 5 days postoperatively. Postoperative examinations included uncorrected distance visual acuity and slitlamp biomicroscopy to assess epithelial defect size. Subjective evaluation of pain and vision was recorded 1, 2, 3, and 4 days postoperatively.
The study enrolled 44 patients (88 eyes). The mean epithelial defect size immediately after surgery was 47.0 mm(2) with both types of bandage contact lenses. There was no statistically significant difference in epithelial defect size between the 2 lenses at any postoperative visit. Three days postoperatively, reepithelialization was complete in 75.0% of eyes in the lotrafilcon A group and 72.7% of the eyes in the lotrafilcon B group.
There were no differences in corneal reepithelialization or subjective measurements after PRK between the 2 types of silicone hydrogel bandage contact lenses.
比较 2 种高透氧性硅水凝胶绷带接触镜在准分子激光角膜切削术(PRK)后的疗效。
克里特大学医学院视光学研究所,希腊克里特岛伊拉克利翁。
在这项前瞻性研究中,44 例(88 只眼)双侧 PRK 患者的 1 只眼随机佩戴 lotrafilcon A(夜戴型和日戴型)绷带接触镜,另 1 只眼佩戴 lotrafilcon B(O(2)Optix)绷带接触镜。患者和检查者均对哪种绷带接触镜类型应用于哪只眼不知情。患者在手术当天以及术后 1、3 和 5 天接受检查。术后检查包括未矫正的远视力和裂隙灯显微镜检查,以评估上皮缺损的大小。术后 1、2、3 和 4 天记录患者的疼痛和视力的主观评估。
该研究纳入了 44 例(88 只眼)患者。两种类型的绷带接触镜在术后即刻的平均上皮缺损大小均为 47.0mm(2)。在任何术后随访中,两种镜片的上皮缺损大小均无统计学差异。术后 3 天,lotrafilcon A 组中 75.0%的眼完全再上皮化,lotrafilcon B 组中 72.7%的眼完全再上皮化。
在 PRK 后,两种硅水凝胶绷带接触镜在角膜再上皮化或主观测量方面无差异。