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比较两种不同隐形眼镜对角膜胶原交联术后角膜再上皮化的影响。

Comparing the effects of two different contact lenses on corneal re-epithelialization after corneal collagen cross-linking.

作者信息

Kocluk Yusuf, Cetinkaya Savas, Sukgen Emine Alyamac, Günay Murat, Mete Alper

机构信息

Yusuf Kocluk, MD. Adana Numune Training and Research Hospital, Ophthalmology Clinic, Adana, Turkey.

Savas Cetinkaya, MD. Adana Numune Training and Research Hospital, Ophthalmology Clinic, Adana, Turkey.

出版信息

Pak J Med Sci. 2017 May-Jun;33(3):680-685. doi: 10.12669/pjms.333.12241.

Abstract

OBJECTIVE

To investigate whether keratoconus (KC) patients who applied the corneal collagen cross-linking (CXL) and two different contact lens (CL) showed any differences in complaints and findings following the CXL.

METHODS

This prospective, comparative, double-blind clinical study involved 60 eyes of 60 patients (38 female and 22 male). At the end of the CXL procedure, CL (Balafilcon A) was inserted in 29 patients (Group-1) while CL with different material content (Hioxifilcon A) designed for therapeutic/bandage purposes were inserted in 31 patients (Group-2).

RESULTS

On the 1 and 3 day after the CXL, there were no statistically significant differences between the groups in terms of the postoperative symptoms. On the 3 day after the CXL, all cases of both two groups were found to complete the corneal re-epithelialization. There was more PE ratio in the patients who had allergic conjunctivitis.

CONCLUSIONS

With the use of Balafilcon A and Hioxifilcon A lens materials, KC patients who underwent the CXL were found to have similar symptoms and clinical findings after the CXL. However, epithelial staining and PE were observed more in KC cases accompanied by allergic conjunctivitis.

摘要

目的

研究接受角膜胶原交联(CXL)治疗的圆锥角膜(KC)患者使用两种不同的隐形眼镜(CL)后,在CXL后的不适主诉和检查结果方面是否存在差异。

方法

这项前瞻性、对比性、双盲临床研究纳入了60例患者(38例女性和22例男性)的60只眼。在CXL手术结束时,29例患者(第1组)植入了CL(Balafilcon A),而31例患者(第2组)植入了具有不同材料成分、用于治疗/包扎目的的CL(Hioxifilcon A)。

结果

在CXL后的第1天和第3天,两组患者的术后症状在统计学上无显著差异。在CXL后的第3天,发现两组所有病例均完成了角膜上皮再形成。过敏性结膜炎患者的角膜上皮糜烂率更高。

结论

使用Balafilcon A和Hioxifilcon A镜片材料后,接受CXL治疗的KC患者在CXL后出现了相似的症状和临床检查结果。然而,在伴有过敏性结膜炎的KC病例中,角膜上皮染色和角膜上皮糜烂更为常见。

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本文引用的文献

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Corneal collagen crosslinking in keratoconus and other eye disease.圆锥角膜及其他眼部疾病中的角膜胶原交联
Int J Ophthalmol. 2015 Apr 18;8(2):407-18. doi: 10.3980/j.issn.2222-3959.2015.02.35. eCollection 2015.
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Curative effect assessment of bandage contact lens in neurogenic keratitis.绷带式隐形眼镜治疗神经源性角膜炎的疗效评估
Int J Ophthalmol. 2014 Dec 18;7(6):980-3. doi: 10.3980/j.issn.2222-3959.2014.06.12. eCollection 2014.
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Adv Ther. 2013 Oct;30(10):858-69. doi: 10.1007/s12325-013-0065-9. Epub 2013 Oct 30.
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J Cataract Refract Surg. 2010 Jan;36(1):186-8; author reply 188-9. doi: 10.1016/j.jcrs.2009.08.019.

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