Lin I-Chan, Wang I-Jong, Lei Mei-Shu, Lin Luke L-K, Hu Fung-Rong
Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan, ROC.
J Cataract Refract Surg. 2008 Aug;34(8):1312-7. doi: 10.1016/j.jcrs.2008.04.028.
To compare vision-related quality of life and higher-order aberrations (HOAs) with an aspherical intraocular lens (IOL) (AcrySof IQ SN60WF) and a conventional spherical IOL (AcrySof SA60AT) (both Alcon) after phacoemulsification.
Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan, Republic of China.
Sixty-five patients were prospectively randomized to receive an Alcon AcrySof IQ SN60WF IOL (30 eyes) or an AcrySof SA60AT IOL (35 eyes). All patients had a complete ophthalmologic examination including uncorrected visual acuity, best spectacle-corrected visual acuity (BSCVA), and wavefront analysis preoperatively and 3 months postoperatively. Patients also completed the National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) to evaluate vision-related quality of life.
The mean postoperative BSCVA (logMAR) was 0.09 +/- 0.07 (SD) in the aspherical IOL group and 0.12 +/- 0.08 in the spherical IOL group; the difference was not statistically significant. Spherical aberrations were statistically significantly lower in the aspherical IOL group (mean 0.12 +/- 0.23 microm) than in the spherical IOL group (mean 0.33 +/- 0.20 microm) (P = .001). Both IOL types improved most aspects of patients' vision-related quality of life. The aspherical IOL group had clinically significant improvement on more NEI VFQ-25 subscales, although the difference between groups in vision-related quality of life was not statistically significant.
Eyes with the aspherical AcrySof IQ SN60WF IOL had reduced HOAs and spherical aberrations compared with eyes with the spherical AcrySof SA60AT IOL; however, there were no statistically significant differences in visual acuity or vision-related quality of life between groups.
比较白内障超声乳化术后使用非球面人工晶状体（IOL）（AcrySof IQ SN60WF）与传统球面IOL（AcrySof SA60AT）（均为爱尔康公司产品）时与视力相关的生活质量和高阶像差（HOAs）。
中国台湾地区台北市台湾大学医院眼科。
65例患者被前瞻性随机分为两组，分别植入爱尔康AcrySof IQ SN60WF IOL（30只眼）或AcrySof SA60AT IOL（35只眼）。所有患者术前及术后3个月均进行了包括未矫正视力、最佳矫正视力（BSCVA）及波前分析在内的全面眼科检查。患者还完成了美国国立眼科研究所视觉功能问卷（NEI VFQ - 25）以评估与视力相关的生活质量。
非球面IOL组术后平均BSCVA（logMAR）为0.09±0.07（标准差），球面IOL组为0.12±0.08；差异无统计学意义。非球面IOL组的球差在统计学上显著低于球面IOL组（平均0.12±0.23微米）（平均0.33±0.20微米）（P = 0.001）。两种IOL类型均改善了患者与视力相关生活质量的大多数方面。非球面IOL组在更多NEI VFQ - 25子量表上有临床显著改善，尽管两组在与视力相关的生活质量方面的差异无统计学意义。
与植入球面AcrySof SA60AT IOL的眼相比，植入非球面AcrySof IQ SN60WF IOL的眼高阶像差和球差降低；然而，两组之间在视力或与视力相关的生活质量方面无统计学显著差异。
