Jog Parag V, Gin Mary S
Roger Adams Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
Org Lett. 2008 Sep 4;10(17):3693-6. doi: 10.1021/ol8013045. Epub 2008 Jul 26.
A gated synthetic ion channel with beta-cyclodextrin as the pore and azobenzene as the gate is reported. Irradiation converts a tethered trans-azobenzene to cis-azobenzene which likely transforms the channel from a self-inclusion complex to a dissociated structure. This transformation results in an increase in anion transport and a decrease in cation transport across a phospholipid vesicle membrane.
报道了一种以β-环糊精为孔道、偶氮苯为门控的门控合成离子通道。光照可将连接的反式偶氮苯转化为顺式偶氮苯，这可能会使通道从自包合复合物转变为解离结构。这种转变导致跨磷脂囊泡膜的阴离子转运增加，阳离子转运减少。
