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肾细胞癌悬雍垂转移导致气道阻塞:不常见的部位。

Renal cell carcinoma uvula metastasis leading to airway compromise: an unusual site.

机构信息

Otolaryngology, Glangwili General Hospital, Carmarthen, UK

Otolaryngology, Glangwili General Hospital, Carmarthen, UK.

出版信息

BMJ Case Rep. 2022 Apr 8;15(4):e248098. doi: 10.1136/bcr-2021-248098.

DOI:10.1136/bcr-2021-248098
PMID:35396238
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8995948/
Abstract

We present a case report of a gentleman presenting with a globular lesion arising from his uvula. Although elective admission was planned, he presented with airway compromise, and emergency excision was required. The patient had a background of metastatic clear cell renal carcinoma; histology confirmed the uvula lesion as a further secondary deposit. Renal cell carcinoma has a recognised metastatic propensity, but spread to the uvula is rare, with only two previously described cases in the literature. This case is notable for the unusual location of the metastasis, as well as the rapid progression of symptoms, which threatened the airway and necessitated urgent surgical intervention.

摘要

我们报告了一例男性患者,其悬雍垂上出现球形病变。虽然计划进行择期入院治疗,但患者出现气道阻塞,需要紧急切除。该患者有转移性透明细胞肾细胞癌病史;组织学证实悬雍垂病变为进一步的继发性转移。肾细胞癌具有公认的转移倾向,但转移至悬雍垂较为罕见,文献中仅描述过两例。该病例的特点是转移部位不常见,以及症状迅速进展,这威胁到气道,需要紧急手术干预。

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本文引用的文献

1
Lymphoma of the Uvula: Clinical, Morphological, Histopathological, and Genetic Characterization. A Nationwide Danish Study From 1980 to 2019.悬雍垂淋巴瘤:临床、形态学、组织病理学及遗传学特征。一项1980年至2019年丹麦全国性研究。
Front Surg. 2021 Apr 30;8:675279. doi: 10.3389/fsurg.2021.675279. eCollection 2021.
2
Epidemiology of Renal Cell Carcinoma.肾细胞癌的流行病学
World J Oncol. 2020 Jun;11(3):79-87. doi: 10.14740/wjon1279. Epub 2020 May 14.
3
Symptomatic oral squamous papilloma of the uvula - a rare incidental finding.悬雍垂有症状的口腔鳞状乳头状瘤——一种罕见的偶然发现。
Malays Fam Physician. 2019 Dec 31;14(3):74-76. eCollection 2019.
4
Atypical metastasis of renal cell carcinoma to the uvula: case report and review of literature.肾细胞癌罕见转移至悬雍垂:病例报告及文献复习
Int Med Case Rep J. 2018 Feb 16;11:29-32. doi: 10.2147/IMCRJ.S147815. eCollection 2018.
5
Renal cell carcinoma: Atypical metastasis to inguinal lymph nodes.肾细胞癌:腹股沟淋巴结的非典型转移
Urol Ann. 2017 Jan-Mar;9(1):80-82. doi: 10.4103/0974-7796.198905.
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Metastasis to the oral soft tissues: A review of 412 cases.口腔软组织转移:412例病例回顾
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Impact of surgical margin clearance for resection of secondary hepatic malignancies.手术切缘阴性对继发性肝恶性肿瘤切除的影响。
J Surg Oncol. 2016 Mar;113(3):289-95. doi: 10.1002/jso.24107. Epub 2015 Dec 10.
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A unique presentation of a renal clear cell carcinoma with atypical metastases.一例具有非典型转移的肾透明细胞癌的独特表现。
Int J Surg Case Rep. 2015;11:29-32. doi: 10.1016/j.ijscr.2015.03.009. Epub 2015 Apr 9.
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Metastatic tumors to the jaws and oral cavity.转移至颌骨和口腔的肿瘤。
J Oral Maxillofac Pathol. 2013 Jan;17(1):71-5. doi: 10.4103/0973-029X.110737.
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Low-grade B-cell lymphoma presenting as a uvular mass.
Ear Nose Throat J. 2012 Dec;91(12):E22-4. doi: 10.1177/014556131209101218.