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一项基于学校的药物滥用预防计划的有效性:欧盟-达普整群随机对照试验。

The effectiveness of a school-based substance abuse prevention program: EU-Dap cluster randomised controlled trial.

作者信息

Faggiano Fabrizio, Galanti Maria Rosaria, Bohrn Karl, Burkhart Gregor, Vigna-Taglianti Federica, Cuomo Luca, Fabiani Leila, Panella Massimiliano, Perez Tatiana, Siliquini Roberta, van der Kreeft Peer, Vassara Maro, Wiborg Gudrun

机构信息

Department of Clinical and Experimental Medicine-Avogadro University, Novara, Italy.

出版信息

Prev Med. 2008 Nov;47(5):537-43. doi: 10.1016/j.ypmed.2008.06.018. Epub 2008 Jul 9.

Abstract

OBJECTIVE

To evaluate the effectiveness of the school-based drug abuse prevention program developed in the EU-Dap study (EUropean Drug Abuse Prevention trial) in preventing the use of tobacco, alcohol and drugs at the post-test.

METHODS

Cluster Randomised Controlled Trial. Seven European countries participated in the study; 170 schools (7079 pupils 12-14 years of age) were randomly assigned to one of three experimental conditions or to a control condition during the school year 2004/2005. A pre-test survey assessing past and current substance use was conducted before the implementation of the program. The program consisted in 12-hour class-based curriculum based on a comprehensive social-influence approach. A post-test survey was carried out in all participating schools, 3 months after the end of the program. The association between program condition and change in substance use at post-test was expressed as adjusted Prevalence Odds Ratio (POR), estimated by multilevel regression model.

RESULTS

Program effects were found for daily cigarette smoking (POR=0.70; 0.52-0.94) and episodes of drunkenness in the past 30 days (POR=0.72; 0.58-0.90 for at least one episode, POR=0.69; 0.48-0.99 for three or more episodes), while effects on Cannabis use in the past 30 days were of marginal statistical significance (POR=0.77; 0.60-1.00). The curriculum was successful in preventing baseline non-smokers or sporadic smokers from moving onto daily smoking, but it was not effective in helping baseline daily smokers to reduce or stop smoking.

CONCLUSION

School curricula based on a comprehensive social-influence model may delay progression to daily smoking and episodes of drunkenness.

摘要

目的

评估在欧盟药物滥用预防试验(EU-Dap研究)中开发的校本药物滥用预防项目在测试后预防烟草、酒精和药物使用方面的效果。

方法

整群随机对照试验。七个欧洲国家参与了该研究;在2004/2005学年,170所学校(7079名12 - 14岁的学生)被随机分配到三种实验条件之一或一个对照条件。在项目实施前进行了一项预测试调查,评估过去和当前的物质使用情况。该项目包括基于综合社会影响方法的12小时课堂课程。在项目结束3个月后,对所有参与学校进行了后测试调查。项目条件与测试后物质使用变化之间的关联以调整后的患病率比值比(POR)表示,通过多水平回归模型估计。

结果

发现该项目对每日吸烟(POR = 0.70;0.52 - 0.94)和过去30天内的醉酒发作有效果(至少一次发作的POR = 0.72;0.58 - 0.90,三次或更多次发作的POR = 0.69;0.48 - 0.99),而对过去30天内大麻使用的影响具有边际统计学意义(POR = 0.77;0.60 - 1.00)。该课程成功地防止了基线非吸烟者或偶尔吸烟者转变为每日吸烟者,但在帮助基线每日吸烟者减少或戒烟方面无效。

结论

基于综合社会影响模型的学校课程可能会延迟向每日吸烟和醉酒发作的进展。

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