金黄色葡萄球菌中SarA、σB和IcaR对细胞间粘附素基因座调节因子（icaR）的调控
Regulation of the intercellular adhesin locus regulator (icaR) by SarA, sigmaB, and IcaR in Staphylococcus aureus.
作者信息
Cerca Nuno, Brooks Jamie L, Jefferson Kimberly K
机构信息
Department of Microbiology and Immunology, Virginia Commonwealth University, P.O. Box 980678, Richmond, VA 23928, USA.
出版信息
J Bacteriol. 2008 Oct;190(19):6530-3. doi: 10.1128/JB.00482-08. Epub 2008 Jul 25.
Abstract
The staphylococcal accessory regulator SarA and the alternative sigma factor sigma(B) have been previously identified as positive regulators, and IcaR as a negative regulator, of icaADBC expression. Here, we show that in Staphylococcus aureus SarA and sigma(B) are also required for icaR expression and that IcaR does not have a significant effect on its own expression.
摘要
葡萄球菌辅助调节因子SarA和替代西格玛因子西格玛B先前已被确定为icaADBC表达的正调节因子，而IcaR为负调节因子。在此，我们表明，在金黄色葡萄球菌中，SarA和西格玛B也是icaR表达所必需的，并且IcaR对其自身表达没有显著影响。
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