Tzvetkov D, Tzanev R
Institute of Hygiene and Occupational Health, Medical Academy, Sofia, Bulgaria.
Med Lav. 1991 Jan-Feb;82(1):3-10.
The influence of middle and high frequency vibrations (50 and 150 Hz) on the fatty acid pattern of structural lipids in white rat liver, kidney, heart, aorta and muscular tissue was studied in a 3-month experiment. The study also examined the fatty acid composition of phospholipids in erythrocyte cell membranes of workers occupationally exposed to vibrations and of patients suffering from vibration disease. Statistically significant changes in the per cent distribution of fatty acids were observed, which were more evident in the liver and kidney of experimental animals, and also after high frequency (150 Hz) vibration exposure. Changes in human subjects were greater in workers exposed to hand-arm vibrations and in patients suffering from vibration disease. Routine and more precise methods are needed to assess occupational risk via determination of the lipid metabolism state in workers exposed to vibrations and in patients suffering from vibration disease.
在一项为期3个月的实验中，研究了中高频振动（50赫兹和150赫兹）对白鼠肝脏、肾脏、心脏、主动脉和肌肉组织中结构脂质脂肪酸模式的影响。该研究还检测了职业性接触振动的工人以及患有振动病的患者红细胞细胞膜中磷脂的脂肪酸组成。观察到脂肪酸百分比分布有统计学意义的变化，在实验动物的肝脏和肾脏中以及高频（150赫兹）振动暴露后更为明显。在接触手臂振动的工人和患有振动病的患者中，人体受试者的变化更大。需要常规和更精确的方法，通过测定接触振动的工人和患有振动病的患者的脂质代谢状态来评估职业风险。
