Tsevtkov D, Charŭkchiev D, Krŭsteva S
Probl Khig. 1980;5:11-21.
The variations in the urinary excretion of half-oxidized metabolites, nonprotein nitrogen and chlorides, serum activities of LDH, MDH and ScDH, liver and kidney himogenates and histomorphologic patterns of liver, kidney and muscle tissue were studied in experimental animals, exposed to high-frequency vibrations - 100 hz. with amplitude 0.1 mm, for 60 days. The probable mechanisms of effect of the vibration factor on urinary half-oxidzed metabolite excretion are discussed. These include increased protein and carbohydrate catabolism, disturbances in the oxidoreduction processes, impairement of oxygen tissue supply, impaired urinary metabolite excretion, ect. It is suggested, after additional examination of haman subjects, to include the parameter "total amount of urinary half-oxidized metabolites" in the complex diagnosis of vibration injury in man.
在暴露于高频振动（100赫兹，振幅0.1毫米）60天的实验动物中，研究了半氧化代谢物、非蛋白氮和氯化物的尿排泄变化、LDH、MDH和ScDH的血清活性、肝和肾匀浆以及肝、肾和肌肉组织的组织形态学模式。讨论了振动因素对尿半氧化代谢物排泄影响的可能机制。这些机制包括蛋白质和碳水化合物分解代谢增加、氧化还原过程紊乱、组织氧供应受损、尿代谢物排泄受损等。建议在对人类受试者进行进一步检查后，将“尿半氧化代谢物总量”参数纳入人类振动损伤的综合诊断中。
